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Sym004-induced EGFR elimination is associated with profound anti-tumor activity in EGFRvIII patient-derived glioblastoma models.
Keir, Stephen T; Chandramohan, Vidyalakshmi; Hemphill, Carlee D; Grandal, Michael M; Melander, Maria Carlsen; Pedersen, Mikkel W; Horak, Ivan D; Kragh, Michael; Desjardins, Annick; Friedman, Henry S; Bigner, Darell D.
Afiliação
  • Keir ST; Preston Robert Tisch Brain Tumor Center at Duke, Department of Neurosurgery, Duke University Medical Center, 3624 DUMC, Baker House, Durham, NC, 27710, USA. Keir0001@mc.duke.edu.
  • Chandramohan V; Preston Robert Tisch Brain Tumor Center at Duke, Department of Neurosurgery, Duke University Medical Center, 3624 DUMC, Baker House, Durham, NC, 27710, USA.
  • Hemphill CD; Preston Robert Tisch Brain Tumor Center at Duke, Department of Neurosurgery, Duke University Medical Center, 3624 DUMC, Baker House, Durham, NC, 27710, USA.
  • Grandal MM; Symphogen A/S, Pederstrupvej 93, 27500, Ballerup, Denmark.
  • Melander MC; Symphogen A/S, Pederstrupvej 93, 27500, Ballerup, Denmark.
  • Pedersen MW; Symphogen A/S, Pederstrupvej 93, 27500, Ballerup, Denmark.
  • Horak ID; Symphogen A/S, Pederstrupvej 93, 27500, Ballerup, Denmark.
  • Kragh M; Symphogen A/S, Pederstrupvej 93, 27500, Ballerup, Denmark.
  • Desjardins A; Preston Robert Tisch Brain Tumor Center at Duke, Department of Neurosurgery, Duke University Medical Center, 3624 DUMC, Baker House, Durham, NC, 27710, USA.
  • Friedman HS; Preston Robert Tisch Brain Tumor Center at Duke, Department of Neurosurgery, Duke University Medical Center, 3624 DUMC, Baker House, Durham, NC, 27710, USA.
  • Bigner DD; Preston Robert Tisch Brain Tumor Center at Duke, Department of Neurosurgery, Duke University Medical Center, 3624 DUMC, Baker House, Durham, NC, 27710, USA.
J Neurooncol ; 138(3): 489-498, 2018 Jul.
Article em En | MEDLINE | ID: mdl-29564747
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Encefálicas / Glioblastoma / Anticorpos Monoclonais / Antineoplásicos Tipo de estudo: Prognostic_studies / Risk_factors_studies Limite: Animals / Female / Humans / Male Idioma: En Ano de publicação: 2018 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Encefálicas / Glioblastoma / Anticorpos Monoclonais / Antineoplásicos Tipo de estudo: Prognostic_studies / Risk_factors_studies Limite: Animals / Female / Humans / Male Idioma: En Ano de publicação: 2018 Tipo de documento: Article