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Enantiomeric neolignans from Picrasma quassioides exhibit distinctive cytotoxicity on hepatic carcinoma cells through ROS generation and apoptosis induction.
Lou, Li-Li; Yao, Guo-Dong; Wang, Jie; Zhao, Wen-Yu; Wang, Xiao-Bo; Huang, Xiao-Xiao; Song, Shao-Jiang.
Afiliação
  • Lou LL; School of Traditional Chinese Materia Medica, Key Laboratory of Structure-Based Drug Design and Discovery, Ministry of Education, Shenyang Pharmaceutical University, Shenyang 110016, People's Republic of China.
  • Yao GD; School of Traditional Chinese Materia Medica, Key Laboratory of Structure-Based Drug Design and Discovery, Ministry of Education, Shenyang Pharmaceutical University, Shenyang 110016, People's Republic of China.
  • Wang J; School of Traditional Chinese Materia Medica, Key Laboratory of Structure-Based Drug Design and Discovery, Ministry of Education, Shenyang Pharmaceutical University, Shenyang 110016, People's Republic of China.
  • Zhao WY; School of Traditional Chinese Materia Medica, Key Laboratory of Structure-Based Drug Design and Discovery, Ministry of Education, Shenyang Pharmaceutical University, Shenyang 110016, People's Republic of China.
  • Wang XB; Chinese People's Liberation Army 210 Hospital, Dalian 116021, People's Republic of China.
  • Huang XX; School of Traditional Chinese Materia Medica, Key Laboratory of Structure-Based Drug Design and Discovery, Ministry of Education, Shenyang Pharmaceutical University, Shenyang 110016, People's Republic of China; Chinese People's Liberation Army 210 Hospital, Dalian 116021, People's Republic of China.
  • Song SJ; School of Traditional Chinese Materia Medica, Key Laboratory of Structure-Based Drug Design and Discovery, Ministry of Education, Shenyang Pharmaceutical University, Shenyang 110016, People's Republic of China. Electronic address: songsj99@163.com.
Bioorg Med Chem Lett ; 28(8): 1263-1268, 2018 05 01.
Article em En | MEDLINE | ID: mdl-29567344
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fenóis / Espécies Reativas de Oxigênio / Apoptose / Lignanas / Picrasma / Antineoplásicos Limite: Humans Idioma: En Ano de publicação: 2018 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fenóis / Espécies Reativas de Oxigênio / Apoptose / Lignanas / Picrasma / Antineoplásicos Limite: Humans Idioma: En Ano de publicação: 2018 Tipo de documento: Article