Serum metabolomics study of nutrient metabolic variations in chronic heat-stressed broilers.
Br J Nutr
; 119(7): 771-781, 2018 04.
Article
em En
| MEDLINE
| ID: mdl-29569538
ABSTRACT
To investigate the effects of heat stress on broiler metabolism, we assigned 144 broilers to normal control (NC), heat stress (HS) or pair-fed (PF) groups and then monitored the effects using growth performance, carcass characteristics, biochemical assays and GC-MS-based metabolomics. The up-regulation of cloacal temperature confirmed that our experiment was successful in inducing chronic heat stress. The average daily gain and average daily feed intake of the HS group were significantly lower than those of the NC group, by 28·76 and 18·42 %, respectively (P1 and P<0·05). The greater feedgain ratio of the HS group was significantly positively correlated with the leg, abdominal fat, subcutaneous fat and intramuscular fat proportions and levels of some free amino acids (proline, l-cysteine, methionine and threonine) but was negatively correlated with breast proportion and levels of some NEFA (stearic acid, arachidonic acid, palmitic acid and oleic acid). These findings indicated that the heat-stressed broilers were in negative energy balance and unable to effectively mobilise fat, thereby resulting in protein decomposition, which subsequently affected growth performance and carcass characteristics.
Palavras-chave
ADFI average daily feed intake; ADG average daily gain; F:G feed:gain ratio; HS heat stress; NC normal control; OPLS-DA orthogonal projections to latent structures discriminant analyses; PF pair-fed; VIP variable importance in the projection; Broilers; Chronic heat stress; GC-MS; Growth performance; Metabolomics
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Galinhas
/
Resposta ao Choque Térmico
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Metabolômica
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Temperatura Alta
Limite:
Animals
Idioma:
En
Ano de publicação:
2018
Tipo de documento:
Article