GE11-Directed Functional Polymersomal Doxorubicin as an Advanced Alternative to Clinical Liposomal Formulation for Ovarian Cancer Treatment.

Zou, Yan; Xia, Yifeng; Meng, Fenghua; Zhang, Jian; Zhong, Zhiyuan

Zou, Yan; Xia, Yifeng; Meng, Fenghua; Zhang, Jian; Zhong, Zhiyuan.

Afiliação

Zou Y; Biomedical Polymers Laboratory, and Jiangsu Key Laboratory of Advanced Functional Polymer Design and Application, College of Chemistry, Chemical Engineering and Materials Science , Soochow University , Suzhou 215123 , P. R. China.
Xia Y; International Joint Centre for Biomedical Innovation, School of Life Sciences , Henan University , Jin Ming Avenue , Kaifeng , Henan 475004 , China.
Meng F; Biomedical Polymers Laboratory, and Jiangsu Key Laboratory of Advanced Functional Polymer Design and Application, College of Chemistry, Chemical Engineering and Materials Science , Soochow University , Suzhou 215123 , P. R. China.
Zhang J; Biomedical Polymers Laboratory, and Jiangsu Key Laboratory of Advanced Functional Polymer Design and Application, College of Chemistry, Chemical Engineering and Materials Science , Soochow University , Suzhou 215123 , P. R. China.
Zhong Z; Biomedical Polymers Laboratory, and Jiangsu Key Laboratory of Advanced Functional Polymer Design and Application, College of Chemistry, Chemical Engineering and Materials Science , Soochow University , Suzhou 215123 , P. R. China.

Mol Pharm ; 15(9): 3664-3671, 2018 09 04.

Article em En | MEDLINE | ID: mdl-29570299

Assuntos

Antibióticos Antineoplásicos/química; Antibióticos Antineoplásicos/uso terapêutico; Doxorrubicina/análogos & derivados; Sistemas de Liberação de Medicamentos/métodos; Lipossomos/química; Peptídeos/química; Animais; Linhagem Celular Tumoral; Doxorrubicina/química; Doxorrubicina/uso terapêutico; Receptores ErbB/metabolismo; Feminino; Humanos; Camundongos; Camundongos Endogâmicos BALB C; Camundongos Nus; Neoplasias Ovarianas/tratamento farmacológico; Polietilenoglicóis/química; Polietilenoglicóis/uso terapêutico; Distribuição Aleatória

Palavras-chave

epidermal growth factor receptor; ovarian cancer; polymersomes; reduction-sensitive; targeted delivery

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Peptídeos / Doxorrubicina / Sistemas de Liberação de Medicamentos / Lipossomos / Antibióticos Antineoplásicos Tipo de estudo: Clinical_trials Limite: Animals / Female / Humans Idioma: En Ano de publicação: 2018 Tipo de documento: Article

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