Quantitative assessment of mAb Fc glycosylation of CQA importance by capillary electrophoresis.

Szigeti, Marton; Chapman, Jeff; Borza, Beata; Guttman, Andras

Szigeti, Marton; Chapman, Jeff; Borza, Beata; Guttman, Andras.

Afiliação

Szigeti M; Horváth Csaba Laboratory of Bioseparation Sciences, Research Centre for Molecular Medicine, Faculty of Medicine, University of Debrecen, Debrecen, Hungary.
Chapman J; Translational Glycomics Research Group, Research Institute for Biomolecular and Chemical Engineering, University of Pannonia, Veszprem, Hungary.
Borza B; SCIEX, Brea, CA, USA.
Guttman A; Horváth Csaba Laboratory of Bioseparation Sciences, Research Centre for Molecular Medicine, Faculty of Medicine, University of Debrecen, Debrecen, Hungary.

Electrophoresis ; 39(18): 2340-2343, 2018 09.

Article em En | MEDLINE | ID: mdl-29600574

Assuntos

Adalimumab/análise; Fragmentos Fc das Imunoglobulinas/química; Asparagina/química; Eletroforese Capilar; Glicosilação; Humanos; Manose/química; Polissacarídeos/química

Palavras-chave

Biotherapeutics; Capillary electrophoresis; Critical quality attributes; Glycosylation; Quantification

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fragmentos Fc das Imunoglobulinas / Adalimumab Limite: Humans Idioma: En Ano de publicação: 2018 Tipo de documento: Article

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google