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Exploring the role of post-translational modifications in regulating α-synuclein interactions by studying the effects of phosphorylation on nanobody binding.
El Turk, Farah; De Genst, Erwin; Guilliams, Tim; Fauvet, Bruno; Hejjaoui, Mirva; Di Trani, Justin; Chiki, Anass; Mittermaier, Anthony; Vendruscolo, Michele; Lashuel, Hilal A; Dobson, Christopher M.
Afiliação
  • El Turk F; Centre for Mosfolding Diseases, Department of Chemistry, University of Cambridge, Cambridge, CB2 1EW, United Kingdom.
  • De Genst E; Department of Chemistry, McGill University, Montreal, Quebec, H3A 2K6, Canada.
  • Guilliams T; Centre for Mosfolding Diseases, Department of Chemistry, University of Cambridge, Cambridge, CB2 1EW, United Kingdom.
  • Fauvet B; Centre for Mosfolding Diseases, Department of Chemistry, University of Cambridge, Cambridge, CB2 1EW, United Kingdom.
  • Hejjaoui M; Laboratory of Molecular and Chemical Biology of Neurodegeneration, Ecole Polytechnique Fédérale de Lausanne, Lausanne, CH 1015, Switzerland.
  • Di Trani J; Laboratory of Molecular and Chemical Biology of Neurodegeneration, Ecole Polytechnique Fédérale de Lausanne, Lausanne, CH 1015, Switzerland.
  • Chiki A; Department of Chemistry, McGill University, Montreal, Quebec, H3A 2K6, Canada.
  • Mittermaier A; Laboratory of Molecular and Chemical Biology of Neurodegeneration, Ecole Polytechnique Fédérale de Lausanne, Lausanne, CH 1015, Switzerland.
  • Vendruscolo M; Department of Chemistry, McGill University, Montreal, Quebec, H3A 2K6, Canada.
  • Lashuel HA; Centre for Mosfolding Diseases, Department of Chemistry, University of Cambridge, Cambridge, CB2 1EW, United Kingdom.
  • Dobson CM; Laboratory of Molecular and Chemical Biology of Neurodegeneration, Ecole Polytechnique Fédérale de Lausanne, Lausanne, CH 1015, Switzerland.
Protein Sci ; 27(7): 1262-1274, 2018 07.
Article em En | MEDLINE | ID: mdl-29603451

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Processamento de Proteína Pós-Traducional / Alfa-Sinucleína / Anticorpos de Domínio Único Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Ano de publicação: 2018 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Processamento de Proteína Pós-Traducional / Alfa-Sinucleína / Anticorpos de Domínio Único Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Ano de publicação: 2018 Tipo de documento: Article