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A novel tropomyosin-related kinase A inhibitor, KK5101 to treat pancreatic cancer.
Fang, Zhenghuan; Han, Boreum; Jung, Kyung Hee; Lee, Ju-Hyeon; El-Damasy, Ashraf Kareem; Gadhe, Changdev G; Kim, Soo Jung; Yan, Hong Hua; Park, Jung Hee; Lee, Ji Eun; Kang, Yeo Wool; Pae, Ae Nim; Keum, Gyochang; Hong, Soon-Sun.
Afiliação
  • Fang Z; Department of Drug Development, College of Medicine, Inha University, 3-ga, Sinheung-dong, Jung-gu, Incheon, 400-712, Republic of Korea.
  • Han B; Department of Drug Development, College of Medicine, Inha University, 3-ga, Sinheung-dong, Jung-gu, Incheon, 400-712, Republic of Korea.
  • Jung KH; Department of Drug Development, College of Medicine, Inha University, 3-ga, Sinheung-dong, Jung-gu, Incheon, 400-712, Republic of Korea.
  • Lee JH; Center for Neuro-Medicine, Brain Science Institute, Korea Institute of Science and Technology, Hwarangro 14-gil 5, Seongbuk-gu, Seoul, 02792, Republic of Korea.
  • El-Damasy AK; Department of Medicinal Chemistry, Faculty of Pharmacy, University of Mansoura, Mansoura, 35516, Egypt.
  • Gadhe CG; Convergence Research Center for Diagnosis, Treatment and Care System of Dementia, Korea Institute of Science and Technology, Hwarangro 14-gil 5, Seongbuk-gu, Seoul, 02792, Republic of Korea.
  • Kim SJ; Department of Drug Development, College of Medicine, Inha University, 3-ga, Sinheung-dong, Jung-gu, Incheon, 400-712, Republic of Korea.
  • Yan HH; Department of Drug Development, College of Medicine, Inha University, 3-ga, Sinheung-dong, Jung-gu, Incheon, 400-712, Republic of Korea.
  • Park JH; Department of Drug Development, College of Medicine, Inha University, 3-ga, Sinheung-dong, Jung-gu, Incheon, 400-712, Republic of Korea.
  • Lee JE; Department of Drug Development, College of Medicine, Inha University, 3-ga, Sinheung-dong, Jung-gu, Incheon, 400-712, Republic of Korea.
  • Kang YW; Department of Drug Development, College of Medicine, Inha University, 3-ga, Sinheung-dong, Jung-gu, Incheon, 400-712, Republic of Korea.
  • Pae AN; Convergence Research Center for Diagnosis, Treatment and Care System of Dementia, Korea Institute of Science and Technology, Hwarangro 14-gil 5, Seongbuk-gu, Seoul, 02792, Republic of Korea.
  • Keum G; Center for Neuro-Medicine, Brain Science Institute, Korea Institute of Science and Technology, Hwarangro 14-gil 5, Seongbuk-gu, Seoul, 02792, Republic of Korea. Electronic address: gkeum@kist.re.kr.
  • Hong SS; Department of Drug Development, College of Medicine, Inha University, 3-ga, Sinheung-dong, Jung-gu, Incheon, 400-712, Republic of Korea. Electronic address: hongs@inha.ac.kr.
Cancer Lett ; 426: 25-36, 2018 07 10.
Article em En | MEDLINE | ID: mdl-29605512
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Pancreáticas / Receptor trkA / Inibidores de Proteínas Quinases Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2018 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Pancreáticas / Receptor trkA / Inibidores de Proteínas Quinases Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2018 Tipo de documento: Article