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Study of the structure-activity relationship of polymyxin analogues.
Kinoshita, Yuhei; Yakushiji, Fumika; Matsui, Hidehito; Hanaki, Hideaki; Ichikawa, Satoshi.
Afiliação
  • Kinoshita Y; Faculty of Pharmaceutical Sciences, Hokkaido University, Kita-12, Nishi-6, Kita-ku, Sapporo 060-0812, Japan.
  • Yakushiji F; Faculty of Pharmaceutical Sciences, Hokkaido University, Kita-12, Nishi-6, Kita-ku, Sapporo 060-0812, Japan; Center for Research and Education on Drug Discovery, Faculty of Pharmaceutical Sciences, Hokkaido University, Kita-12, Nishi-6, Kita-ku, Sapporo 060-0812, Japan.
  • Matsui H; Kitasato Institute for Life Sciences and Graduate School of Infection Control Sciences, Kitasato University, 5-9-1, Shirokane, Minato-ku, Tokyo 108-8641, Japan.
  • Hanaki H; Kitasato Institute for Life Sciences and Graduate School of Infection Control Sciences, Kitasato University, 5-9-1, Shirokane, Minato-ku, Tokyo 108-8641, Japan.
  • Ichikawa S; Faculty of Pharmaceutical Sciences, Hokkaido University, Kita-12, Nishi-6, Kita-ku, Sapporo 060-0812, Japan; Center for Research and Education on Drug Discovery, Faculty of Pharmaceutical Sciences, Hokkaido University, Kita-12, Nishi-6, Kita-ku, Sapporo 060-0812, Japan. Electronic address: ichikawa@
Bioorg Med Chem Lett ; 28(16): 2713-2716, 2018 09 01.
Article em En | MEDLINE | ID: mdl-29606572
ABSTRACT
A structure-activity relationship study on three classes of polymyxin analogues focusing on hydrophobicity was conducted.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Pseudomonas aeruginosa / Polimixinas / Antibacterianos Idioma: En Ano de publicação: 2018 Tipo de documento: Article
Texto completo
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PubMed Links
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Pseudomonas aeruginosa / Polimixinas / Antibacterianos Idioma: En Ano de publicação: 2018 Tipo de documento: Article