Zinc-finger protein 471 suppresses gastric cancer through transcriptionally repressing downstream oncogenic PLS3 and TFAP2A.

Cao, Lei; Wang, Shiyan; Zhang, Yanquan; Wong, Ka-Chun; Nakatsu, Geicho; Wang, Xiaohong; Wong, Sunny; Ji, Jiafu; Yu, Jun

Cao, Lei; Wang, Shiyan; Zhang, Yanquan; Wong, Ka-Chun; Nakatsu, Geicho; Wang, Xiaohong; Wong, Sunny; Ji, Jiafu; Yu, Jun.

Afiliação

Cao L; Institute of Digestive Disease and Department of Medicine and Therapeutics, State Key laboratory of Digestive Disease, Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong, Hong Kong, China.
Wang S; Institute of Digestive Disease and Department of Medicine and Therapeutics, State Key laboratory of Digestive Disease, Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong, Hong Kong, China.
Zhang Y; Institute of Digestive Disease and Department of Medicine and Therapeutics, State Key laboratory of Digestive Disease, Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong, Hong Kong, China.
Wong KC; Department of Computer Science, City University of Hong Kong-Kowloon Tong, Hong Kong, China.
Nakatsu G; Institute of Digestive Disease and Department of Medicine and Therapeutics, State Key laboratory of Digestive Disease, Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong, Hong Kong, China.
Wang X; Key laboratory of Carcinogenesis and Translational Research (Ministry of Education), Department of Gastrointestinal Surgery, Beijing Cancer Hospital and Institute, Beijing, China.
Wong S; Institute of Digestive Disease and Department of Medicine and Therapeutics, State Key laboratory of Digestive Disease, Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong, Hong Kong, China.
Ji J; Key laboratory of Carcinogenesis and Translational Research (Ministry of Education), Department of Gastrointestinal Surgery, Beijing Cancer Hospital and Institute, Beijing, China.
Yu J; Institute of Digestive Disease and Department of Medicine and Therapeutics, State Key laboratory of Digestive Disease, Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong, Hong Kong, China. junyu@cuhk.edu.hk.

Oncogene ; 37(26): 3601-3616, 2018 06.

Article em En | MEDLINE | ID: mdl-29610526

Assuntos

Genes Supressores de Tumor; Glicoproteínas de Membrana/metabolismo; Proteínas dos Microfilamentos/metabolismo; Proteínas Repressoras/metabolismo; Neoplasias Gástricas/patologia; Fator de Transcrição AP-2/metabolismo; Proteína 28 com Motivo Tripartido/metabolismo; Dedos de Zinco/genética; Animais; Apoptose/genética; Linhagem Celular Tumoral; Movimento Celular/genética; Proliferação de Células/genética; Regulação para Baixo/genética; Células HEK293; Humanos; Masculino; Glicoproteínas de Membrana/biossíntese; Glicoproteínas de Membrana/genética; Metilação; Camundongos; Camundongos Endogâmicos BALB C; Camundongos Nus; Proteínas dos Microfilamentos/biossíntese; Proteínas dos Microfilamentos/genética; Invasividade Neoplásica/genética; Transplante de Neoplasias; Regiões Promotoras Genéticas/genética; Interferência de RNA; RNA Interferente Pequeno/genética; Proteínas Repressoras/genética; Neoplasias Gástricas/genética; Neoplasias Gástricas/mortalidade; Fator de Transcrição AP-2/biossíntese; Fator de Transcrição AP-2/genética; Transplante Heterólogo; Proteína 28 com Motivo Tripartido/genética

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas Repressoras / Neoplasias Gástricas / Glicoproteínas de Membrana / Genes Supressores de Tumor / Dedos de Zinco / Fator de Transcrição AP-2 / Proteína 28 com Motivo Tripartido / Proteínas dos Microfilamentos Tipo de estudo: Prognostic_studies Limite: Animals / Humans / Male Idioma: En Ano de publicação: 2018 Tipo de documento: Article

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