Comparison of an <i>In Vitro</i> Diagnostic Next-Generation Sequencing Assay with Sanger Sequencing for HIV-1 Genotypic Resistance Testing.

Tzou, Philip L; Ariyaratne, Pramila; Varghese, Vici; Lee, Charlie; Rakhmanaliev, Elian; Villy, Carolin; Yee, Meiqi; Tan, Kevin; Michel, Gerd; Pinsky, Benjamin A; Shafer, Robert W

Comparison of an In Vitro Diagnostic Next-Generation Sequencing Assay with Sanger Sequencing for HIV-1 Genotypic Resistance Testing.

Tzou, Philip L; Ariyaratne, Pramila; Varghese, Vici; Lee, Charlie; Rakhmanaliev, Elian; Villy, Carolin; Yee, Meiqi; Tan, Kevin; Michel, Gerd; Pinsky, Benjamin A; Shafer, Robert W.

Afiliação

Tzou PL; Division of Infectious Diseases, Stanford University School of Medicine, Stanford, California, USA philiptz@stanford.edu rshafer@stanford.edu.
Ariyaratne P; Vela Diagnostics, Singapore Science Park II, Singapore.
Varghese V; Division of Infectious Diseases, Stanford University School of Medicine, Stanford, California, USA.
Lee C; Vela Diagnostics, Singapore Science Park II, Singapore.
Rakhmanaliev E; Vela Diagnostics, Singapore Science Park II, Singapore.
Villy C; Vela Diagnostics, Singapore Science Park II, Singapore.
Yee M; Vela Diagnostics, Singapore Science Park II, Singapore.
Tan K; Vela Diagnostics, Singapore Science Park II, Singapore.
Michel G; Vela Diagnostics, Singapore Science Park II, Singapore.
Pinsky BA; Division of Infectious Diseases, Stanford University School of Medicine, Stanford, California, USA.
Shafer RW; Department of Pathology, Stanford University School of Medicine, Stanford, California, USA.

J Clin Microbiol ; 56(6)2018 06.

Article em En | MEDLINE | ID: mdl-29618499

Assuntos

Farmacorresistência Viral/genética; HIV-1/genética; Sequenciamento de Nucleotídeos em Larga Escala/métodos; Mutação/genética; Fármacos Anti-HIV/uso terapêutico; Genótipo; Infecções por HIV/tratamento farmacológico; Infecções por HIV/virologia; Integrase de HIV/genética; Transcriptase Reversa do HIV/genética; Humanos; Testes de Sensibilidade Microbiana; RNA Viral/genética; Kit de Reagentes para Diagnóstico; Carga Viral

Palavras-chave

antiviral drug resistance; human immunodeficiency virus; integrase; mutations; next-generation sequencing; proteases; reverse transcriptase

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: HIV-1 / Farmacorresistência Viral / Sequenciamento de Nucleotídeos em Larga Escala / Mutação Tipo de estudo: Diagnostic_studies Limite: Humans Idioma: En Ano de publicação: 2018 Tipo de documento: Article

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