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Tyrosine kinase inhibition effects of novel Pyrazolo[1,5-a]pyrimidines and Pyrido[2,3-d]pyrimidines ligand: Synthesis, biological screening and molecular modeling studies.
El Sayed, Mardia T; Hussein, Hoda A R; Elebiary, Nora M; Hassan, Ghada S; Elmessery, Shahenda M; Elsheakh, Ahmed R; Nayel, Mohamed; Abdel-Aziz, Hatem A.
Afiliação
  • El Sayed MT; Deparment of Applied Organic Chemistry, National Research Centre, 12622 Dokki, Egypt.
  • Hussein HAR; Department of Photochemistry, National Research Centre, 12622 Dokki, Egypt.
  • Elebiary NM; Department of Green Chemistry, National Research Centre, 12622 Dokki, Egypt.
  • Hassan GS; Department of Medicinal Chemistry, Faculty of Pharmacy, Mansoura University, 35516 Mansoura, Egypt. Electronic address: ghadasameh@mans.edu.eg.
  • Elmessery SM; Department of Pharmaceutical Organic Chemistry, Faculty of Pharmacy, Mansoura University, 35516 Mansoura, Egypt.
  • Elsheakh AR; Department of Pharmacology and Toxicology, Faculty of Pharmacy, Mansoura University, 35516 Mansoura, Egypt.
  • Nayel M; National Cancer Institute, Chemotherapeutic Agents Repository, Fisher BioServices, Germantown, MD 20874, USA.
  • Abdel-Aziz HA; Deparment of Applied Organic Chemistry, National Research Centre, 12622 Dokki, Egypt.
Bioorg Chem ; 78: 312-323, 2018 08.
Article em En | MEDLINE | ID: mdl-29625271
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Pirazóis / Piridinas / Pirimidinas / Proteínas Tirosina Quinases / Inibidores de Proteínas Quinases / Antineoplásicos Tipo de estudo: Diagnostic_studies / Screening_studies Limite: Humans Idioma: En Ano de publicação: 2018 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Pirazóis / Piridinas / Pirimidinas / Proteínas Tirosina Quinases / Inibidores de Proteínas Quinases / Antineoplásicos Tipo de estudo: Diagnostic_studies / Screening_studies Limite: Humans Idioma: En Ano de publicação: 2018 Tipo de documento: Article