S6K1 controls epigenetic plasticity for the expression of pancreatic &#945;/ß cell marker genes.

Yi, Sang Ah; Lee, Jieun; Park, Jong Woo; Han, Jihoon; Lee, Min Gyu; Nam, Ki Hong; Park, Jee Hun; Oh, Hwamok; Ahn, Sung Jin; Kim, Saetbyul; Kwon, So Hee; Jo, Dong-Gyu; Han, Jeung-Whan

S6K1 controls epigenetic plasticity for the expression of pancreatic α/ß cell marker genes.

Yi, Sang Ah; Lee, Jieun; Park, Jong Woo; Han, Jihoon; Lee, Min Gyu; Nam, Ki Hong; Park, Jee Hun; Oh, Hwamok; Ahn, Sung Jin; Kim, Saetbyul; Kwon, So Hee; Jo, Dong-Gyu; Han, Jeung-Whan.

Afiliação

Yi SA; School of Pharmacy, Sungkyunkwan University, Suwon, Republic of Korea.
Lee J; School of Pharmacy, Sungkyunkwan University, Suwon, Republic of Korea.
Park JW; School of Pharmacy, Sungkyunkwan University, Suwon, Republic of Korea.
Han J; School of Pharmacy, Sungkyunkwan University, Suwon, Republic of Korea.
Lee MG; School of Pharmacy, Sungkyunkwan University, Suwon, Republic of Korea.
Nam KH; School of Pharmacy, Sungkyunkwan University, Suwon, Republic of Korea.
Park JH; School of Pharmacy, Sungkyunkwan University, Suwon, Republic of Korea.
Oh H; School of Pharmacy, Sungkyunkwan University, Suwon, Republic of Korea.
Ahn SJ; School of Pharmacy, Sungkyunkwan University, Suwon, Republic of Korea.
Kim S; School of Pharmacy, Sungkyunkwan University, Suwon, Republic of Korea.
Kwon SH; College of Pharmacy, Yonsei Institute of Pharmaceutical Sciences, Yonsei University, Incheon, Republic of Korea.
Jo DG; School of Pharmacy, Sungkyunkwan University, Suwon, Republic of Korea.
Han JW; School of Pharmacy, Sungkyunkwan University, Suwon, Republic of Korea.

J Cell Biochem ; 119(8): 6674-6683, 2018 08.

Article em En | MEDLINE | ID: mdl-29665055

Assuntos

Antígenos de Diferenciação/biossíntese; Epigênese Genética; Células Secretoras de Glucagon/metabolismo; Células Secretoras de Insulina/metabolismo; Proteínas Quinases S6 Ribossômicas 90-kDa/metabolismo; Transcrição Gênica; Animais; Antígenos de Diferenciação/genética; Células Secretoras de Glucagon/citologia; Células Secretoras de Insulina/citologia; Camundongos; Camundongos Mutantes; Proteínas Quinases S6 Ribossômicas 90-kDa/genética

Palavras-chave

S6 kinase 1; epigenetic regulation; histone modifications; insulin; pancreatic ß cell; type 1 diabetes mellitus

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Transcrição Gênica / Antígenos de Diferenciação / Proteínas Quinases S6 Ribossômicas 90-kDa / Epigênese Genética / Células Secretoras de Glucagon / Células Secretoras de Insulina Limite: Animals Idioma: En Ano de publicação: 2018 Tipo de documento: Article

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