The Influence of Abdominal and Ectopic Fat Accumulation on Carotid Intima-Media Thickness: A Chongqing Study.
J Stroke Cerebrovasc Dis
; 27(7): 1992-1997, 2018 Jul.
Article
em En
| MEDLINE
| ID: mdl-29673615
ABSTRACT
BACKGROUND:
To investigate the effects of abdominal obesity (AO) and nonalcoholic fatty liver disease (NAFLD) with or without AO on carotid arteries by determining carotid intima-media thickness (CIMT).METHODS:
A total of 2745 Chinese Han adults (aged between 40 and 50 years old) were recruited and divided into 4 groups (1) NW-no NAFL group the normal body weight without NAFLD (n = 1888); (2) AO-no NAFL group AO without NAFLD (n = 259); (3) NW-with NAFL group NAFLD without AO (n = 93); and (4) AO-with NAFL group AO with NAFLD (n = 505). The CIMT rate of each group was compared among 4 groups and the regression analysis was further used to correct confounders.RESULTS:
We found that the NW-with NAFL group had a significantly higher CIMT rate than the AO-no NAFL group ([.87 ± .31] versus [.72 ± .29] P < .01) and the AO-with NAFL group ([.87 ± .31] versus [.79 ± .26], P < .01).CONCLUSIONS:
The ectopic liver fat accumulation may increase the risk of atherosclerosis. Therefore, screening NAFLD in the population with normal weight may be beneficial for the prevention of atherosclerosis at an early stage.Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Artérias Carótidas
/
Obesidade Abdominal
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Espessura Intima-Media Carotídea
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Hepatopatia Gordurosa não Alcoólica
Tipo de estudo:
Diagnostic_studies
/
Etiology_studies
/
Risk_factors_studies
Limite:
Adult
/
Female
/
Humans
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Male
/
Middle aged
País/Região como assunto:
Asia
Idioma:
En
Ano de publicação:
2018
Tipo de documento:
Article