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Discovery and Optimization of Potent and CNS Penetrant M5-Preferring Positive Allosteric Modulators Derived from a Novel, Chiral N-(Indanyl)piperidine Amide Scaffold.
Bender, Aaron M; Cho, Hyekyung P; Nance, Kellie D; Lingenfelter, Kaelyn S; Luscombe, Vincent B; Gentry, Patrick R; Voigtritter, Karl; Berizzi, Alice E; Sexton, Patrick M; Langmead, Christopher J; Christopoulos, Arthur; Locuson, Charles W; Bridges, Thomas M; Chang, Sichen; O'Neill, Jordan C; Zhan, Xiaoyan; Niswender, Colleen M; Jones, Carrie K; Conn, P Jeffrey; Lindsley, Craig W.
Afiliação
  • Berizzi AE; Drug Discovery Biology, Monash Institute of Pharmaceutical Sciences , Monash University , Parkville , Victoria 3052 , Australia.
  • Sexton PM; Drug Discovery Biology, Monash Institute of Pharmaceutical Sciences , Monash University , Parkville , Victoria 3052 , Australia.
  • Langmead CJ; Drug Discovery Biology, Monash Institute of Pharmaceutical Sciences , Monash University , Parkville , Victoria 3052 , Australia.
  • Christopoulos A; Drug Discovery Biology, Monash Institute of Pharmaceutical Sciences , Monash University , Parkville , Victoria 3052 , Australia.
ACS Chem Neurosci ; 9(7): 1572-1581, 2018 07 18.
Article em En | MEDLINE | ID: mdl-29678111
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Colinérgicos Limite: Animals / Humans / Male Idioma: En Ano de publicação: 2018 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Colinérgicos Limite: Animals / Humans / Male Idioma: En Ano de publicação: 2018 Tipo de documento: Article