Red meat and processed meat intake and risk for cutaneous melanoma in white women and men: Two prospective cohort studies.
J Am Acad Dermatol
; 79(2): 252-257.e6, 2018 Aug.
Article
em En
| MEDLINE
| ID: mdl-29698709
ABSTRACT
BACKGROUND:
Red and processed meat consumption has been associated with increased risk for several cancers, but the association with cutaneous melanoma risk has been inconclusive.OBJECTIVE:
To investigate the association between red and processed meat intake and melanoma risk.METHODS:
Dietary information was assessed by using food frequency questionnaires in 2 prospective cohorts 75,263 women from the Nurses' Health Study (1984-2010) and 48,523 men from the Health Professionals Follow-up Study (1986-2010). Melanoma cases were confirmed by reviewing pathology records. Pooled multivariable hazard ratios and 95% confidence intervals were estimated by using Cox proportional hazards models.RESULTS:
A total of 679 female and 639 male melanoma cases were documented during follow-up. Red and processed meat intake was inversely associated with melanoma risk (P = .002 for trend); the pooled hazard ratios (95% confidence intervals) of the 2 cohorts were 1.00 (reference), 1.00 (0.87-1.14), 0.98 (0.86-1.13), 0.89 (0.77-1.02), and 0.81 (0.70-0.95) for increasing quintiles of intake.LIMITATIONS:
Findings might have limited generalizability, considering that the cohorts were limited to white health professionals.CONCLUSION:
Red and processed meat intake was inversely associated with melanoma risk in these 2 cohorts.Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Neoplasias Cutâneas
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População Branca
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Dieta
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Carne Vermelha
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Produtos da Carne
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Melanoma
Tipo de estudo:
Etiology_studies
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Observational_studies
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Prognostic_studies
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Risk_factors_studies
Limite:
Adult
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Female
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Humans
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Male
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Middle aged
Idioma:
En
Ano de publicação:
2018
Tipo de documento:
Article