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[Correlation of molecular weight and nanofiltration mass transfer coefficient of phenolic acid composition from Salvia miltiorrhiza].
Li, Cun-Yu; Wu, Xin; Gu, Jia-Mei; Li, Hong-Yang; Peng, Guo-Ping.
Afiliação
  • Li CY; College of Pharmacy, Nanjing University of Chinese Medicine, Nanjing 210023, China.
  • Wu X; Jiangsu Collaborative Innovation Center of Chinese Medicinal Resources Industrialization, Nanjing 210023, China.
  • Gu JM; College of Pharmacy, Nanjing University of Chinese Medicine, Nanjing 210023, China.
  • Li HY; College of Pharmacy, Nanjing University of Chinese Medicine, Nanjing 210023, China.
  • Peng GP; College of Pharmacy, Nanjing University of Chinese Medicine, Nanjing 210023, China.
Zhongguo Zhong Yao Za Zhi ; 43(7): 1453-1458, 2018 Apr.
Article em Zh | MEDLINE | ID: mdl-29728036
ABSTRACT
Based on the molecular sieving and solution-diffusion effect in nanofiltration separation, the correlation between initial concentration and mass transfer coefficient of three typical phenolic acids from Salvia miltiorrhiza was fitted to analyze the relationship among mass transfer coefficient, molecular weight and concentration. The experiment showed a linear relationship between operation pressure and membrane flux. Meanwhile, the membrane flux was gradually decayed with the increase of solute concentration. On the basis of the molecular sieving and solution-diffusion effect, the mass transfer coefficient and initial concentration of three phenolic acids showed a power function relationship, and the regression coefficients were all greater than 0.9. The mass transfer coefficient and molecular weight of three phenolic acids were negatively correlated with each other, and the order from high to low is protocatechualdehyde >rosmarinic acid> salvianolic acid B. The separation mechanism of nanofiltration for phenolic acids was further clarified through the analysis of the correlation of molecular weight and nanofiltration mass transfer coefficient. The findings provide references for nanofiltration separation, especially for traditional Chinese medicine with phenolic acids.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Salvia miltiorrhiza / Hidroxibenzoatos Idioma: Zh Ano de publicação: 2018 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Salvia miltiorrhiza / Hidroxibenzoatos Idioma: Zh Ano de publicação: 2018 Tipo de documento: Article