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Accessing the Open PHACTS Discovery Platform with Workflow Tools.
Digles, Daniela; Caracoti, Andrei; Jacoby, Edgar.
Afiliação
  • Digles D; Department of Pharmaceutical Chemistry, University of Vienna, Vienna, Austria. daniela.digles@univie.ac.at.
  • Caracoti A; BIOVIA, A Dassault Systèmes Brand, Cambridge, UK.
  • Jacoby E; Janssen Research and Development, Beerse, Belgium.
Methods Mol Biol ; 1787: 183-193, 2018.
Article em En | MEDLINE | ID: mdl-29736719
The Open PHACTS Discovery Platform integrates several public databases, which can be of interest when annotating the results of a phenotypic screening campaign. Workflow tools provide easy-to-customize possibilities to access the platform. Here, we describe how to create such workflows for two different workflow tools (KNIME and Pipeline Pilot), including a protocol to annotate compounds (e.g., phenotypic screening hits) with compound classification, known protein targets, and classifications of the targets.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Software / Biologia Computacional / Descoberta de Drogas Idioma: En Ano de publicação: 2018 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Software / Biologia Computacional / Descoberta de Drogas Idioma: En Ano de publicação: 2018 Tipo de documento: Article