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Specific targeting of point mutations in EGFR L858R-positive lung cancer by CRISPR/Cas9.
Cheung, Alvin Ho-Kwan; Chow, Chit; Zhang, Jinglin; Zhou, Yuhang; Huang, Tingting; Ng, Kayla Ching-Kei; Or, Terry Cho-Tsun; Yao, Yoyo Yao; Dong, Yujuan; Fung, Jackie Mei-Wah; Xiong, Lei; Chan, Aden Ka-Yin; Lung, Wai-Ming Raymond; Kang, Wei; To, Ka-Fai.
Afiliação
  • Cheung AH; Department of Anatomical and Cellular Pathology, State Key Laboratory of Oncology in South China, Prince of Wales Hospital, The Chinese University of Hong Kong, Hong Kong, China.
  • Chow C; Department of Anatomical and Cellular Pathology, State Key Laboratory of Oncology in South China, Prince of Wales Hospital, The Chinese University of Hong Kong, Hong Kong, China.
  • Zhang J; Department of Anatomical and Cellular Pathology, State Key Laboratory of Oncology in South China, Prince of Wales Hospital, The Chinese University of Hong Kong, Hong Kong, China.
  • Zhou Y; Institute of Digestive Disease, Partner State Key Laboratory of Digestive Disease, The Chinese University of Hong Kong, Hong Kong, China.
  • Huang T; Li Ka Shing Institute of Health Science, Sir Y.K. Pao Cancer Center, The Chinese University of Hong Kong, Hong Kong, China.
  • Ng KC; Department of Anatomical and Cellular Pathology, State Key Laboratory of Oncology in South China, Prince of Wales Hospital, The Chinese University of Hong Kong, Hong Kong, China.
  • Or TC; Institute of Digestive Disease, Partner State Key Laboratory of Digestive Disease, The Chinese University of Hong Kong, Hong Kong, China.
  • Yao YY; Li Ka Shing Institute of Health Science, Sir Y.K. Pao Cancer Center, The Chinese University of Hong Kong, Hong Kong, China.
  • Dong Y; Department of Anatomical and Cellular Pathology, State Key Laboratory of Oncology in South China, Prince of Wales Hospital, The Chinese University of Hong Kong, Hong Kong, China.
  • Fung JM; Institute of Digestive Disease, Partner State Key Laboratory of Digestive Disease, The Chinese University of Hong Kong, Hong Kong, China.
  • Xiong L; Li Ka Shing Institute of Health Science, Sir Y.K. Pao Cancer Center, The Chinese University of Hong Kong, Hong Kong, China.
  • Chan AK; Shenzhen Research Institute, The Chinese University of Hong Kong, Shenzhen, China.
  • Lung WR; Department of Anatomical and Cellular Pathology, State Key Laboratory of Oncology in South China, Prince of Wales Hospital, The Chinese University of Hong Kong, Hong Kong, China.
  • Kang W; Department of Anatomical and Cellular Pathology, State Key Laboratory of Oncology in South China, Prince of Wales Hospital, The Chinese University of Hong Kong, Hong Kong, China.
  • To KF; Department of Anatomical and Cellular Pathology, State Key Laboratory of Oncology in South China, Prince of Wales Hospital, The Chinese University of Hong Kong, Hong Kong, China.
Lab Invest ; 98(7): 968-976, 2018 07.
Article em En | MEDLINE | ID: mdl-29748615

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Terapia Genética / Mutação Puntual / Sistemas CRISPR-Cas / Receptores ErbB / Neoplasias Pulmonares Limite: Humans Idioma: En Ano de publicação: 2018 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Terapia Genética / Mutação Puntual / Sistemas CRISPR-Cas / Receptores ErbB / Neoplasias Pulmonares Limite: Humans Idioma: En Ano de publicação: 2018 Tipo de documento: Article