Stress-related salivary proteins affect the production of volatile sulfur compounds by oral bacteria.
Oral Dis
; 24(7): 1358-1366, 2018 Oct.
Article
em En
| MEDLINE
| ID: mdl-29761905
ABSTRACT
OBJECTIVE:
To determine whether stress-related substances and sex hormones influence the growth and in vitro production of volatile sulfur compounds (VSCs) by Solobacterium moorei and Fusobacterium nucleatum. MATERIALS ANDMETHODS:
Bacteria growth and VSCs production were evaluated in the presence of alpha-amylase, beta-defensin-2, mucin, estradiol, and progesterone. Growth was evaluated by colony counting, and the production of the VSCs hydrogen sulfide (H2 S) and methyl mercaptan (CH3 SH) was measured using the Oral Chroma™ instrument.RESULTS:
Mucin induced the production of H2 S by both bacteria, but had a slight inhibitory effect on CH3 SH production by F. nucleatum. It also increased the viability of F. nucleatum. Alpha-amylase increased H2 S production by S. moorei and CH3 SH production by F. nucleatum, but had no effect on H2 S production by F. nucleatum. No substance altered the viability of S. moorei. No effects of beta-defensin-2, estradiol, or progesterone were observed.CONCLUSION:
The salivary stress-related proteins mucin and alpha-amylase altered VSCs production by F. nucleatum and S. moorei, favoring H2 S production. These findings are a step toward understanding the relation between stress and increased amounts of H2 S.Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Proteínas e Peptídeos Salivares
/
Compostos de Sulfidrila
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Fusobacterium nucleatum
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Bactérias Gram-Positivas
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Sulfeto de Hidrogênio
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Boca
Limite:
Humans
Idioma:
En
Ano de publicação:
2018
Tipo de documento:
Article