Temporal and tissue-specific variability of SMN protein levels in mouse models of spinal muscular atrophy.

Groen, Ewout J N; Perenthaler, Elena; Courtney, Natalie L; Jordan, Crispin Y; Shorrock, Hannah K; van der Hoorn, Dinja; Huang, Yu-Ting; Murray, Lyndsay M; Viero, Gabriella; Gillingwater, Thomas H

Groen, Ewout J N; Perenthaler, Elena; Courtney, Natalie L; Jordan, Crispin Y; Shorrock, Hannah K; van der Hoorn, Dinja; Huang, Yu-Ting; Murray, Lyndsay M; Viero, Gabriella; Gillingwater, Thomas H.

Afiliação

Groen EJN; Centre for Discovery Brain Sciences, Edinburgh Medical School: Biomedical Sciences.
Perenthaler E; Euan MacDonald Centre for Motor Neurone Disease Research, University of Edinburgh, Edinburgh EH8 9XD, UK.
Courtney NL; Centre for Discovery Brain Sciences, Edinburgh Medical School: Biomedical Sciences.
Jordan CY; Euan MacDonald Centre for Motor Neurone Disease Research, University of Edinburgh, Edinburgh EH8 9XD, UK.
Shorrock HK; Centre for Discovery Brain Sciences, Edinburgh Medical School: Biomedical Sciences.
van der Hoorn D; Euan MacDonald Centre for Motor Neurone Disease Research, University of Edinburgh, Edinburgh EH8 9XD, UK.
Huang YT; Centre for Discovery Brain Sciences, Edinburgh Medical School: Biomedical Sciences.
Murray LM; Centre for Discovery Brain Sciences, Edinburgh Medical School: Biomedical Sciences.
Viero G; Euan MacDonald Centre for Motor Neurone Disease Research, University of Edinburgh, Edinburgh EH8 9XD, UK.
Gillingwater TH; Centre for Discovery Brain Sciences, Edinburgh Medical School: Biomedical Sciences.

Hum Mol Genet ; 27(16): 2851-2862, 2018 08 15.

Article em En | MEDLINE | ID: mdl-29790918

Assuntos

Atrofia Muscular Espinal/genética; Proteína 1 de Sobrevivência do Neurônio Motor/genética; Processamento Alternativo/genética; Animais; Modelos Animais de Doenças; Éxons; Humanos; Camundongos; Neurônios Motores/metabolismo; Neurônios Motores/patologia; Atrofia Muscular Espinal/fisiopatologia; Splicing de RNA/genética; Medula Espinal/fisiopatologia; Proteína 2 de Sobrevivência do Neurônio Motor/genética

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Atrofia Muscular Espinal / Proteína 1 de Sobrevivência do Neurônio Motor Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2018 Tipo de documento: Article

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