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Management of the blood supply for a Jk(a-b-) patient with an anti-Jk3 in preparation for an urgent heart transplant: An illustrative example of a successful international cooperation.
Thonier, V; Cohen-Bacrie, S; Loussert, I; Thornton, N; Djoudi, R; Woimant, G; Boulat, C; Pirenne, F; Peyrard, T.
Afiliação
  • Thonier V; Institut national de la transfusion sanguine (INTS), département Centre national de référence pour les groupes sanguins (CNRGS), 75011 Paris, France. Electronic address: vthonier@ints.fr.
  • Cohen-Bacrie S; Établissement français du sang Île-de-France, banque nationale de sang de phénotype rare, 94010 Créteil, France.
  • Loussert I; Établissement français du sang Île-de-France, site de Bichat, 75877 Paris, France.
  • Thornton N; International Blood Group Reference Laboratory, NHS Blood and Transplant, Bristol, United Kingdom.
  • Djoudi R; Établissement français du sang, siège national, 93218 Saint-Denis, France.
  • Woimant G; Établissement français du sang Île-de-France, site de Cabanel, 75015 Paris, France.
  • Boulat C; Établissement français du sang, siège national, 93218 Saint-Denis, France.
  • Pirenne F; Établissement français du sang Île-de-France, banque nationale de sang de phénotype rare, 94010 Créteil, France; Unité Inserm U955, équipe 2, université Paris Est Créteil, 94010 Créteil, France; Laboratoire d'excellence GR-Ex, 75015 Paris, France.
  • Peyrard T; Institut national de la transfusion sanguine (INTS), département Centre national de référence pour les groupes sanguins (CNRGS), 75011 Paris, France; Laboratoire d'excellence GR-Ex, 75015 Paris, France; UMR_S1134 Inserm, Université Paris Diderot, 75015 Paris, France.
Transfus Clin Biol ; 26(1): 48-55, 2019 Feb.
Article em En | MEDLINE | ID: mdl-29802018
The Kidd blood group system currently comprises two polymorphic and antithetical antigens, Jka and Jkb, and one high-prevalence antigen, Jk3. Jknull individuals do not express any of the Kidd antigens, and are at risk of developing an anti-Jk3 which is known to be dangerous and responsible for acute or delayed hemolytic transfusion reaction. We report a case of an immunized Jknull patient, who was scheduled to undergo a heart transplant. In order to organize his blood provision management, two conference calls were held between the clinical team and the different staff involved in this challenging blood supply. In light of the blood needs, the available resources, and the constraints, a mix of fresh and frozen units were used. As the supply from France was not sufficient, Finland and New Zealand provided the majority of the fresh units. We report here how this international supply chain was organized, including the difficulties that we encountered. Anticipation, communication and flexibility were essential in making this heart transplant possible without needing to transfuse incompatible units.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Transfusão de Sangue / Cuidados Pré-Operatórios / Cooperação Internacional / Sistema do Grupo Sanguíneo Kidd Tipo de estudo: Risk_factors_studies Limite: Humans / Male / Middle aged País/Região como assunto: Europa Idioma: En Ano de publicação: 2019 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Transfusão de Sangue / Cuidados Pré-Operatórios / Cooperação Internacional / Sistema do Grupo Sanguíneo Kidd Tipo de estudo: Risk_factors_studies Limite: Humans / Male / Middle aged País/Região como assunto: Europa Idioma: En Ano de publicação: 2019 Tipo de documento: Article