Evaluation index for asymmetric ventricular size on brain magnetic resonance images in very low birth weight infants.
Brain Dev
; 40(9): 753-759, 2018 Oct.
Article
em En
| MEDLINE
| ID: mdl-29807844
ABSTRACT
OBJECTIVE:
Asymmetric ventriculomegaly is often evident on brain magnetic resonance imaging (MRI) in very low birth weight infants (VLBWI) and is interpreted as white matter injury. However, no evaluation index for asymmetric left-right and anterior-posterior ventricular sizes has been established.METHODS:
In this retrospective multicenter cohort study, brain T2-weighted MRI was performed at term-equivalent ages in 294 VLBWI born between 2009 and 2011. The value of a lateral ventricular index (LVI) to evaluate asymmetric ventricular size, as well as the relationship between the LVI value and walking at a corrected age of 18â¯months was investigated. At the level of the foramen of Monro in a horizontal slice, asymmetry between the left and right sides and between the anterior and posterior horns was identified by the corrected width and was detected by a low concordance rate and κ statistic value. An LVI representing the sum of the widths of the four horns of the lateral ventricle corrected for cerebral diameter was devised.RESULTS:
Asymmetric left-right and anterior-posterior ventricular sizes were confirmed. The LVI value was significantly higher in the non-walking VLBWI group (nâ¯=â¯39) than in the walking VLBWI group (nâ¯=â¯255; 18.2 vs. 15.8, pâ¯=â¯0.02). An LVI cut-off value of 21.5 was associated with non-walking. Multivariate analysis revealed that an LVI value >21.5 was an independent predictor of walking disability at the corrected age of 18â¯months (odds ratio 2.56, pâ¯=â¯0.008).CONCLUSIONS:
The LVI value calculated via MRI may predict walking disability at a corrected age of 18â¯months in VLBWI.Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Encéfalo
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Imageamento por Ressonância Magnética
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Recém-Nascido de muito Baixo Peso
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Hidrocefalia
Tipo de estudo:
Diagnostic_studies
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Observational_studies
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Prognostic_studies
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Risk_factors_studies
Limite:
Female
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Humans
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Male
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Newborn
Idioma:
En
Ano de publicação:
2018
Tipo de documento:
Article