The independent effects of hypovolaemia and pulmonary vasoconstriction on ventricular function and exercise capacity during acclimatisation to 3800 m.

Stembridge, Mike; Ainslie, Philip N; Boulet, Lindsey M; Anholm, James; Subedi, Prajan; Tymko, Michael M; Willie, Christopher K; Cooper, Stephen-Mark; Shave, Rob

The independent effects of hypovolaemia and pulmonary vasoconstriction on ventricular function and exercise capacity during acclimatisation to 3800 m.

Stembridge, Mike; Ainslie, Philip N; Boulet, Lindsey M; Anholm, James; Subedi, Prajan; Tymko, Michael M; Willie, Christopher K; Cooper, Stephen-Mark; Shave, Rob.

Afiliação

Stembridge M; Cardiff Centre for Exercise and Health, Cardiff Metropolitan University, Cardiff, UK.
Ainslie PN; Centre for Heart Lung and Vascular Health, University of British Columbia, Kelowna, BC, Canada.
Boulet LM; Centre for Heart Lung and Vascular Health, University of British Columbia, Kelowna, BC, Canada.
Anholm J; VA Loma Linda Healthcare System and Loma Linda University School of Medicine, Loma Linda, CA, USA.
Subedi P; VA Loma Linda Healthcare System and Loma Linda University School of Medicine, Loma Linda, CA, USA.
Tymko MM; Centre for Heart Lung and Vascular Health, University of British Columbia, Kelowna, BC, Canada.
Willie CK; Centre for Heart Lung and Vascular Health, University of British Columbia, Kelowna, BC, Canada.
Cooper SM; Cardiff Centre for Exercise and Health, Cardiff Metropolitan University, Cardiff, UK.
Shave R; Cardiff Centre for Exercise and Health, Cardiff Metropolitan University, Cardiff, UK.

J Physiol ; 597(4): 1059-1072, 2019 02.

Article em En | MEDLINE | ID: mdl-29808473

Assuntos

Altitude; Tolerância ao Exercício; Hipovolemia/fisiopatologia; Hipóxia/fisiopatologia; Pulmão/irrigação sanguínea; Vasoconstrição; Função Ventricular; Aclimatação; Adulto; Diástole; Humanos; Pulmão/fisiologia; Pulmão/fisiopatologia; Masculino; Artéria Pulmonar/efeitos dos fármacos; Artéria Pulmonar/fisiologia; Artéria Pulmonar/fisiopatologia; Citrato de Sildenafila/farmacologia; Vasodilatadores/farmacologia

Palavras-chave

cardiac function; diastolic function; high altitude; hypovolemia; hypoxia; left ventricular mechanics; pulmonary hypertension; pulmonary vasoconstriction

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Vasoconstrição / Função Ventricular / Tolerância ao Exercício / Hipovolemia / Altitude / Pulmão / Hipóxia Tipo de estudo: Clinical_trials Limite: Adult / Humans / Male Idioma: En Ano de publicação: 2019 Tipo de documento: Article

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