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Enhanced catalytic activities and modified substrate preferences for taxoid 10ß-O-acetyl transferase mutants by engineering catalytic histidine residues.
You, Lin-Feng; Huang, Jia-Jun; Wei, Tao; Lin, Shu-Ling; Jiang, Bing-Hua; Guo, Li-Qiong; Lin, Jun-Fang.
Afiliação
  • You LF; College of Food Science & Institute of Food Biotechnology, South China Agricultural University, Guangzhou, 510640, Guangdong, China.
  • Huang JJ; Chongqing Key Laboratory of Catalysis and Functional Organic Molecule, Chongqing Technology and Business University, Chongqing, 400067, China.
  • Wei T; College of Food Science & Institute of Food Biotechnology, South China Agricultural University, Guangzhou, 510640, Guangdong, China.
  • Lin SL; College of Food Science & Institute of Food Biotechnology, South China Agricultural University, Guangzhou, 510640, Guangdong, China.
  • Jiang BH; Research Center for Micro-Ecological Agent Engineering and Technology of Guangdong Province, Guangzhou, 510640, Guangdong, China.
  • Guo LQ; College of Food Science & Institute of Food Biotechnology, South China Agricultural University, Guangzhou, 510640, Guangdong, China.
  • Lin JF; Department of Pathology, Anatomy and Cell Biology, Thomas Jefferson University, Philadelphia, PA, 19107, USA.
Biotechnol Lett ; 40(8): 1245-1251, 2018 Aug.
Article em En | MEDLINE | ID: mdl-29869304
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Acetilesterase / Proteínas Recombinantes / Mutagênese Sítio-Dirigida / Taxoides / Histidina Idioma: En Ano de publicação: 2018 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Acetilesterase / Proteínas Recombinantes / Mutagênese Sítio-Dirigida / Taxoides / Histidina Idioma: En Ano de publicação: 2018 Tipo de documento: Article