Bioengineered intravaginal isolate of Lactobacillus plantarum expresses algal lectin scytovirin demonstrating anti-HIV-1 activity.

Janahi, Essam Mohammed Ahmed; Haque, Shafiul; Akhter, Naseem; Wahid, Mohd; Jawed, Arshad; Mandal, Raju Kumar; Lohani, Mohtashim; Areeshi, Mohammed Yahya; Almalki, Shaia; Das, Shukla; Dar, Sajad Ahmad

Janahi, Essam Mohammed Ahmed; Haque, Shafiul; Akhter, Naseem; Wahid, Mohd; Jawed, Arshad; Mandal, Raju Kumar; Lohani, Mohtashim; Areeshi, Mohammed Yahya; Almalki, Shaia; Das, Shukla; Dar, Sajad Ahmad.

Afiliação

Janahi EMA; Department of Biology, College of Science, University of Bahrain, Sakhir, Bahrain. Electronic address: emohammed@uob.edu.bh.
Haque S; Research and Scientific Studies Unit, College of Nursing & Allied Health Sciences, University of Jazan, Jazan, Saudi Arabia.
Akhter N; Department of Laboratory Medicine, Faculty of Applied Medical Sciences, Albaha University, Albaha, Saudi Arabia.
Wahid M; Research and Scientific Studies Unit, College of Nursing & Allied Health Sciences, University of Jazan, Jazan, Saudi Arabia.
Jawed A; Research and Scientific Studies Unit, College of Nursing & Allied Health Sciences, University of Jazan, Jazan, Saudi Arabia.
Mandal RK; Research and Scientific Studies Unit, College of Nursing & Allied Health Sciences, University of Jazan, Jazan, Saudi Arabia.
Lohani M; Department of EMS, College of Applied Medical Sciences, University of Jazan, Jazan, Saudi Arabia.
Areeshi MY; Research and Scientific Studies Unit, College of Nursing & Allied Health Sciences, University of Jazan, Jazan, Saudi Arabia.
Almalki S; Department of Laboratory Medicine, Faculty of Applied Medical Sciences, Albaha University, Albaha, Saudi Arabia.
Das S; Department of Microbiology, University College of Medical Sciences (University of Delhi) & GTB Hospital, Delhi, India.
Dar SA; Research and Scientific Studies Unit, College of Nursing & Allied Health Sciences, University of Jazan, Jazan, Saudi Arabia; Department of Microbiology, University College of Medical Sciences (University of Delhi) & GTB Hospital, Delhi, India. Electronic address: sdar@jazanu.edu.sa.

Microb Pathog ; 122: 1-6, 2018 Sep.

Article em En | MEDLINE | ID: mdl-29870744

Assuntos

Antivirais/farmacologia; Proteínas de Bactérias/farmacologia; Proteínas de Transporte/farmacologia; Infecções por HIV/prevenção & controle; HIV-1/efeitos dos fármacos; Lactobacillus plantarum/metabolismo; Lectinas/farmacologia; Proteínas Recombinantes/farmacologia; Internalização do Vírus/efeitos dos fármacos; Antivirais/metabolismo; Proteínas de Bactérias/genética; Proteínas de Bactérias/metabolismo; Proteínas de Transporte/genética; Proteínas de Transporte/metabolismo; Linhagem Celular; Efeito Citopatogênico Viral; HIV-1/fisiologia; Humanos; Lactobacillus plantarum/genética; Lectinas/genética; Lectinas/metabolismo; Proteínas de Membrana; Proteínas Recombinantes/genética; Proteínas Recombinantes/metabolismo

Palavras-chave

Cervico-vaginal mucosa; HIV; Lactobacillus; Scytovirin; Virucide

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Antivirais / Proteínas de Bactérias / Proteínas Recombinantes / Proteínas de Transporte / Infecções por HIV / HIV-1 / Lactobacillus plantarum / Internalização do Vírus / Lectinas Limite: Humans Idioma: En Ano de publicação: 2018 Tipo de documento: Article

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