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Biochemical mechanisms implemented by human acute myeloid leukemia cells to suppress host immune surveillance.
Yasinska, Inna M; Gonçalves Silva, Isabel; Sakhnevych, Svetlana; Gibbs, Bernhard F; Raap, Ulrike; Fasler-Kan, Elizaveta; Sumbayev, Vadim V.
Afiliação
  • Yasinska IM; Medway School of Pharmacy, Universities of Kent and Greenwich, Chatham Maritime, UK.
  • Gonçalves Silva I; Medway School of Pharmacy, Universities of Kent and Greenwich, Chatham Maritime, UK.
  • Sakhnevych S; Medway School of Pharmacy, Universities of Kent and Greenwich, Chatham Maritime, UK.
  • Gibbs BF; Department of Dermatology and Allergy, University of Oldenburg, Oldenburg, Germany.
  • Raap U; Department of Dermatology and Allergy, University of Oldenburg, Oldenburg, Germany.
  • Fasler-Kan E; Department of Pediatric Surgery and Department of Biomedical Research, Children's Hospital, Inselspital, University of Bern, Bern, Switzerland.
  • Sumbayev VV; Department of Biomedicine University Hospital Basel and University of Basel, Basel, Switzerland.
Cell Mol Immunol ; 15(11): 989-991, 2018 11.
Article em En | MEDLINE | ID: mdl-29872115
ABSTRACT
Acute myeloid leukaemia (AML) is a blood/bone marrow cancer originating from myeloid cell precusors capable of self-renewing. AML cells implement biochemical mechanisms which allow them not only to survive, but also to successfully escape immune surveillance. ln this work, we discuss crucial molecular mechanisms used by human AML cells in order to evade immune attack.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Leucemia Mieloide Aguda / Evasão Tumoral Tipo de estudo: Screening_studies Limite: Humans Idioma: En Ano de publicação: 2018 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Leucemia Mieloide Aguda / Evasão Tumoral Tipo de estudo: Screening_studies Limite: Humans Idioma: En Ano de publicação: 2018 Tipo de documento: Article