Niemann-Pick C1-deficient mice lacking sterol O-acyltransferase 2 have less hepatic cholesterol entrapment and improved liver function.

Lopez, Adam M; Jones, Ryan D; Repa, Joyce J; Turley, Stephen D

Lopez, Adam M; Jones, Ryan D; Repa, Joyce J; Turley, Stephen D.

Afiliação

Lopez AM; Department of Internal Medicine, University of Texas Southwestern Medical Center , Dallas, Texas.
Jones RD; Department of Physiology, University of Texas Southwestern Medical Center , Dallas, Texas.
Repa JJ; Department of Internal Medicine, University of Texas Southwestern Medical Center , Dallas, Texas.
Turley SD; Department of Physiology, University of Texas Southwestern Medical Center , Dallas, Texas.

Am J Physiol Gastrointest Liver Physiol ; 315(4): G454-G463, 2018 10 01.

Article em En | MEDLINE | ID: mdl-29878847

Assuntos

Colesterol/metabolismo; Fígado/metabolismo; Proteína C1 de Niemann-Pick/deficiência; Esterol O-Aciltransferase/genética; Alanina Transaminase/metabolismo; Animais; Aspartato Aminotransferases/metabolismo; Feminino; Fígado/fisiopatologia; Masculino; Camundongos; Camundongos Endogâmicos BALB C; Esterol O-Aciltransferase/metabolismo; Esterol O-Aciltransferase 2

Palavras-chave

esterified cholesterol; hepatomegaly; lysosomal storage disease; transaminase activity; unesterified cholesterol

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Colesterol / Esterol O-Aciltransferase / Proteína C1 de Niemann-Pick / Fígado Limite: Animals Idioma: En Ano de publicação: 2018 Tipo de documento: Article

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