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The ATR Inhibitor AZD6738 Synergizes with Gemcitabine In Vitro and In Vivo to Induce Pancreatic Ductal Adenocarcinoma Regression.
Wallez, Yann; Dunlop, Charles R; Johnson, Timothy Isaac; Koh, Siang-Boon; Fornari, Chiara; Yates, James W T; Bernaldo de Quirós Fernández, Sandra; Lau, Alan; Richards, Frances M; Jodrell, Duncan I.
Afiliação
  • Wallez Y; Cancer Research UK Cambridge Institute, University of Cambridge, Cambridge, United Kingdom. Yann.Wallez@cruk.cam.ac.uk Fran.Richards@cruk.cam.ac.uk.
  • Dunlop CR; Cancer Research UK Cambridge Institute, University of Cambridge, Cambridge, United Kingdom.
  • Johnson TI; Cancer Research UK Cambridge Institute, University of Cambridge, Cambridge, United Kingdom.
  • Koh SB; Cancer Research UK Cambridge Institute, University of Cambridge, Cambridge, United Kingdom.
  • Fornari C; Massachusetts General Hospital Cancer Center, Boston, Massachusetts.
  • Yates JWT; Harvard Medical School, Boston, Massachusetts.
  • Bernaldo de Quirós Fernández S; Safety and ADME Translational Sciences Department, Drug Safety and Metabolism, IMED Biotech Unit, AstraZeneca, Cambridge, United Kingdom.
  • Lau A; Oncology, IMED Biotech Unit, AstraZeneca, Cambridge, United Kingdom.
  • Richards FM; Cancer Research UK Cambridge Institute, University of Cambridge, Cambridge, United Kingdom.
  • Jodrell DI; Oncology, IMED Biotech Unit, AstraZeneca, Cambridge, United Kingdom.
Mol Cancer Ther ; 17(8): 1670-1682, 2018 08.
Article em En | MEDLINE | ID: mdl-29891488
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Pirimidinas / Sulfóxidos / Adenocarcinoma / Carcinoma Ductal Pancreático / Desoxicitidina / Antimetabólitos Antineoplásicos Limite: Animals / Humans Idioma: En Ano de publicação: 2018 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Pirimidinas / Sulfóxidos / Adenocarcinoma / Carcinoma Ductal Pancreático / Desoxicitidina / Antimetabólitos Antineoplásicos Limite: Animals / Humans Idioma: En Ano de publicação: 2018 Tipo de documento: Article