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Statins enhance efficacy of venetoclax in blood cancers.
Lee, J Scott; Roberts, Andrew; Juarez, Dennis; Vo, Thanh-Trang T; Bhatt, Shruti; Herzog, Lee-Or; Mallya, Sharmila; Bellin, Richard J; Agarwal, Suresh K; Salem, Ahmed Hamed; Xu, Tu; Jia, Jia; Li, Lingxiao; Hanna, John R; Davids, Matthew S; Fleischman, Angela G; O'Brien, Susan; Lam, Lloyd T; Leverson, Joel D; Letai, Anthony; Schatz, Jonathan H; Fruman, David A.
Afiliação
  • Lee JS; Department of Molecular Biology and Biochemistry, University of California, Irvine, Irvine, CA 92697, USA.
  • Roberts A; Oncology Development, AbbVie Inc., North Chicago, IL 60064, USA. dfruman@uci.edu awroberts@comcast.net.
  • Juarez D; Department of Molecular Biology and Biochemistry, University of California, Irvine, Irvine, CA 92697, USA.
  • Vo TT; Department of Molecular Biology and Biochemistry, University of California, Irvine, Irvine, CA 92697, USA.
  • Bhatt S; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02215, USA.
  • Herzog LO; Department of Molecular Biology and Biochemistry, University of California, Irvine, Irvine, CA 92697, USA.
  • Mallya S; Department of Molecular Biology and Biochemistry, University of California, Irvine, Irvine, CA 92697, USA.
  • Bellin RJ; Oncology Development, AbbVie Inc., North Chicago, IL 60064, USA.
  • Agarwal SK; Oncology Development, AbbVie Inc., North Chicago, IL 60064, USA.
  • Salem AH; Oncology Development, AbbVie Inc., North Chicago, IL 60064, USA.
  • Xu T; Department of Clinical Pharmacy, Faculty of Pharmacy, Ain Shams University, Cairo 11566, Egypt.
  • Jia J; Oncology Development, AbbVie Inc., North Chicago, IL 60064, USA.
  • Li L; Oncology Development, AbbVie Inc., North Chicago, IL 60064, USA.
  • Hanna JR; Department of Medicine, Sylvester Comprehensive Cancer Center, University of Miami Miller School of Medicine, Miami, FL 33136, USA.
  • Davids MS; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02215, USA.
  • Fleischman AG; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02215, USA.
  • O'Brien S; Department of Medicine, University of California, Irvine, Irvine, CA 92697, USA.
  • Lam LT; Department of Medicine, University of California, Irvine, Irvine, CA 92697, USA.
  • Leverson JD; Oncology Development, AbbVie Inc., North Chicago, IL 60064, USA.
  • Letai A; Oncology Development, AbbVie Inc., North Chicago, IL 60064, USA.
  • Schatz JH; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02215, USA.
  • Fruman DA; Department of Medicine, Sylvester Comprehensive Cancer Center, University of Miami Miller School of Medicine, Miami, FL 33136, USA.
Sci Transl Med ; 10(445)2018 06 13.
Article em En | MEDLINE | ID: mdl-29899021
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Sulfonamidas / Compostos Bicíclicos Heterocíclicos com Pontes / Inibidores de Hidroximetilglutaril-CoA Redutases / Antineoplásicos Tipo de estudo: Observational_studies / Risk_factors_studies Limite: Animals / Female / Humans / Male Idioma: En Ano de publicação: 2018 Tipo de documento: Article
Texto completo
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PubMed Links
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Sulfonamidas / Compostos Bicíclicos Heterocíclicos com Pontes / Inibidores de Hidroximetilglutaril-CoA Redutases / Antineoplásicos Tipo de estudo: Observational_studies / Risk_factors_studies Limite: Animals / Female / Humans / Male Idioma: En Ano de publicação: 2018 Tipo de documento: Article