Endothelial cells are critical regulators of iron transport in a model of the human blood-brain barrier.

Chiou, Brian; Neal, Emma H; Bowman, Aaron B; Lippmann, Ethan S; Simpson, Ian A; Connor, James R

Chiou, Brian; Neal, Emma H; Bowman, Aaron B; Lippmann, Ethan S; Simpson, Ian A; Connor, James R.

Afiliação

Chiou B; Department of Neurosurgery, Penn State College of Medicine, Hershey, PA, USA.
Neal EH; Department of Chemical and Biomolecular Engineering, Vanderbilt University, Nashville, TN, USA.
Bowman AB; Department of Pediatrics, Vanderbilt University Medical Center, Nashville, TN, USA.
Lippmann ES; Department of Neurology, Vanderbilt University Medical Center, Nashville, TN, USA.
Simpson IA; Department of Biochemistry, Vanderbilt University Medical Center, Nashville, TN, USA.
Connor JR; Department of Chemical and Biomolecular Engineering, Vanderbilt University, Nashville, TN, USA.

J Cereb Blood Flow Metab ; 39(11): 2117-2131, 2019 11.

Article em En | MEDLINE | ID: mdl-29911470

Assuntos

Barreira Hematoencefálica/metabolismo; Células Endoteliais/metabolismo; Ferro/metabolismo; Apoferritinas/metabolismo; Transporte Biológico; Encéfalo/metabolismo; Proteínas de Transporte de Cátions/metabolismo; Células Cultivadas; Células Endoteliais/fisiologia; Hepcidinas/metabolismo; Homeostase; Humanos; Modelos Biológicos; Doenças Neurodegenerativas/metabolismo; Transferrina/metabolismo

Palavras-chave

Bloodbrain barrier; H-ferritin; iron; transferrin; transferrin receptor

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Barreira Hematoencefálica / Células Endoteliais / Ferro Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Ano de publicação: 2019 Tipo de documento: Article

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