Organic Solute Transporter &#945;-ß Protects Ileal Enterocytes From Bile Acid-Induced Injury.

Ferrebee, Courtney B; Li, Jianing; Haywood, Jamie; Pachura, Kimberly; Robinson, Brian S; Hinrichs, Benjamin H; Jones, Rheinallt M; Rao, Anuradha; Dawson, Paul A

Organic Solute Transporter α-ß Protects Ileal Enterocytes From Bile Acid-Induced Injury.

Ferrebee, Courtney B; Li, Jianing; Haywood, Jamie; Pachura, Kimberly; Robinson, Brian S; Hinrichs, Benjamin H; Jones, Rheinallt M; Rao, Anuradha; Dawson, Paul A.

Afiliação

Ferrebee CB; Department of Pediatrics, Division of Gastroenterology, Hepatology, and Nutrition, Emory University, Atlanta, Georgia.
Li J; Department of Internal Medicine, Wake Forest School of Medicine, Winston-Salem, North Carolina.
Haywood J; Department of Pediatrics, Division of Gastroenterology, Hepatology, and Nutrition, Emory University, Atlanta, Georgia.
Pachura K; Department of Internal Medicine, Wake Forest School of Medicine, Winston-Salem, North Carolina.
Robinson BS; Department of Pediatrics, Division of Gastroenterology, Hepatology, and Nutrition, Emory University, Atlanta, Georgia.
Hinrichs BH; Department of Pathology, Emory University, Atlanta, Georgia.
Jones RM; Department of Pathology, Emory University, Atlanta, Georgia.
Rao A; Department of Pediatrics, Division of Gastroenterology, Hepatology, and Nutrition, Emory University, Atlanta, Georgia.
Dawson PA; Department of Pediatrics, Division of Gastroenterology, Hepatology, and Nutrition, Emory University, Atlanta, Georgia.

Cell Mol Gastroenterol Hepatol ; 5(4): 499-522, 2018.

Article em En | MEDLINE | ID: mdl-29930976

Palavras-chave

ARE, anti-oxidant response element; Asbt, apical sodium-dependent bile acid transporter; CDCA, chenodeoxycholic acid; Drosophila; FGF, fibroblast growth factor; FXR, farnesoid X receptor; GAPDH, glyceraldehyde-3-phosphate dehydrogenase; GFP, green fluorescence protein; GSH, reduced glutathione; GSSG, oxidized glutathione; Ibabp, ileal bile acid binding protein; Ileum; NEC, necrotizing enterocolitis; Neonate; Nox, reduced nicotinamide adenine dinucleotide phosphate oxidase; Nrf2, nuclear factor (erythroid-derived 2)-like 2; Nuclear Factor Erythroid-Derived 2-Like 2; Ost, organic solute transporter; PBS, phosphate-buffered saline; ROS, reactive oxygen species; Reactive Oxygen Species; TNF, tumor necrosis factor; TUNEL, terminal deoxynucleotidyl transferasemediated deoxyuridine triphosphate nick-end labeling; WT, wild type; cRNA, complementary RNA; mRNA, messenger RNA

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Ano de publicação: 2018 Tipo de documento: Article

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Ano de publicação: 2018 Tipo de documento: Article