Knockdown of MicroRNA-21 Promotes Neurological Recovery After Acute Spinal Cord Injury.

Xie, Wei; Yang, Shang-You; Zhang, Qianqian; Zhou, Yadong; Wang, Yi; Liu, Ronghan; Wang, Wenzhao; Shi, Jixue; Ning, Bin; Jia, Tanghong

Xie, Wei; Yang, Shang-You; Zhang, Qianqian; Zhou, Yadong; Wang, Yi; Liu, Ronghan; Wang, Wenzhao; Shi, Jixue; Ning, Bin; Jia, Tanghong.

Afiliação

Xie W; Department Spinal Surgery, Jinan Central Hospital Affiliated to Shandong University, 105 Jiefang Road, Jinan, 250013, Shandong, China.
Yang SY; Department Emergency Medicine, Taishan Medical University, Taian, 271016, Shandong, China.
Zhang Q; Department Surgery - Orthopedics, University of Kansas School of Medicine-Wichita, Wichita, KS, 67214, USA.
Zhou Y; Department Obstetrics and Gynecology, Affiliated Hospital of Taishan Medical University, Taian, 271000, Shandong, China.
Wang Y; Department Emergency Medicine, Taishan Medical University, Taian, 271016, Shandong, China.
Liu R; Department Ophthalmology, Affiliated Hospital of Taishan Medical University, Taian, 271000, Shandong, China.
Wang W; Department Spinal Surgery, Jinan Central Hospital Affiliated to Shandong University, 105 Jiefang Road, Jinan, 250013, Shandong, China.
Shi J; Department Spinal Surgery, Jinan Central Hospital Affiliated to Shandong University, 105 Jiefang Road, Jinan, 250013, Shandong, China.
Ning B; Department Emergency Medicine, Taishan Medical University, Taian, 271016, Shandong, China.
Jia T; Department Spinal Surgery, Jinan Central Hospital Affiliated to Shandong University, 105 Jiefang Road, Jinan, 250013, Shandong, China. ningbin@sdu.edu.cn.

Neurochem Res ; 43(8): 1641-1649, 2018 Aug.

Article em En | MEDLINE | ID: mdl-29934690

Assuntos

MicroRNAs/genética; Regeneração Nervosa/genética; Traumatismos da Medula Espinal/terapia; Animais; Fator Neurotrófico Derivado do Encéfalo/genética; Citocinas/metabolismo; Feminino; Regulação da Expressão Gênica/genética; Técnicas de Silenciamento de Genes; Terapia Genética/métodos; Camundongos Endogâmicos C57BL; Proteínas Proto-Oncogênicas c-akt/metabolismo; RNA Mensageiro/genética; Transdução de Sinais/fisiologia; Medula Espinal/patologia; Traumatismos da Medula Espinal/patologia

Palavras-chave

MiR-21; Mouse; Signaling pathway; Spinal cord injury

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Traumatismos da Medula Espinal / MicroRNAs / Regeneração Nervosa Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Ano de publicação: 2018 Tipo de documento: Article

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