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A new medermycin analog from the marine-derived actinomycetes Streptomyces sp. ZS-A45.
Huang, Yun; Jiang, Qing; Chen, Yu-Hong; Zhang, Da-Shan; Ding, Wan-Jing; Ma, Zhong-Jun.
Afiliação
  • Huang Y; a Institute of Marine Biology , Ocean College, Zhejiang University , Zhoushan 316021 , China.
  • Jiang Q; a Institute of Marine Biology , Ocean College, Zhejiang University , Zhoushan 316021 , China.
  • Chen YH; a Institute of Marine Biology , Ocean College, Zhejiang University , Zhoushan 316021 , China.
  • Zhang DS; a Institute of Marine Biology , Ocean College, Zhejiang University , Zhoushan 316021 , China.
  • Ding WJ; a Institute of Marine Biology , Ocean College, Zhejiang University , Zhoushan 316021 , China.
  • Ma ZJ; a Institute of Marine Biology , Ocean College, Zhejiang University , Zhoushan 316021 , China.
J Asian Nat Prod Res ; 21(8): 826-831, 2019 Aug.
Article em En | MEDLINE | ID: mdl-29947258
ABSTRACT
A new medermycin analog (1) was isolated from the marine-derived actinomycetes Streptomyces sp. ZS-A45. The structure elucidation of compound 1 was determined by the HRESIMS and extensive NMR analysis. And compound 1 exhibited significant cytotoxicity against PC3 cell lines with IC50 values of 0.81 ± 0.42 µm.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Actinobacteria / Antibacterianos Limite: Humans Idioma: En Ano de publicação: 2019 Tipo de documento: Article
Texto completo
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XML
PubMed Links
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Actinobacteria / Antibacterianos Limite: Humans Idioma: En Ano de publicação: 2019 Tipo de documento: Article