Chemotherapy-generated cell debris stimulates colon carcinoma tumor growth via osteopontin.

Chang, Jaimie; Bhasin, Swati S; Bielenberg, Diane R; Sukhatme, Vikas P; Bhasin, Manoj; Huang, Sui; Kieran, Mark W; Panigrahy, Dipak

Chang, Jaimie; Bhasin, Swati S; Bielenberg, Diane R; Sukhatme, Vikas P; Bhasin, Manoj; Huang, Sui; Kieran, Mark W; Panigrahy, Dipak.

Afiliação

Chang J; Center for Vascular Biology Research, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, USA.
Bhasin SS; Department of Pathology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, USA.
Bielenberg DR; Cancer Center, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, USA.
Sukhatme VP; Division of Interdisciplinary Medicine and Biology, Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, USA.
Bhasin M; Vascular Biology Program, Boston Children's Hospital, Harvard Medical School, Boston, Massachusetts, USA.
Huang S; Department of Surgery, Harvard Medical School, Boston, Massachusetts, USA.
Kieran MW; Cancer Center, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, USA.
Panigrahy D; Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, USA.

FASEB J ; 33(1): 114-125, 2019 01.

Article em En | MEDLINE | ID: mdl-29957058

Assuntos

Neoplasias do Colo/patologia; Fluoruracila/farmacologia; Neovascularização Patológica/patologia; Osteopontina/metabolismo; Animais; Antimetabólitos Antineoplásicos/farmacologia; Apoptose; Proliferação de Células; Neoplasias do Colo/tratamento farmacológico; Neoplasias do Colo/metabolismo; Humanos; Macrófagos/efeitos dos fármacos; Macrófagos/metabolismo; Macrófagos/patologia; Masculino; Camundongos; Neovascularização Patológica/tratamento farmacológico; Neovascularização Patológica/metabolismo; Prognóstico; Taxa de Sobrevida; Células Tumorais Cultivadas; Ensaios Antitumorais Modelo de Xenoenxerto

Palavras-chave

angiogenesis; cancer; macrophage

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias do Colo / Osteopontina / Fluoruracila / Neovascularização Patológica Tipo de estudo: Prognostic_studies Limite: Animals / Humans / Male Idioma: En Ano de publicação: 2019 Tipo de documento: Article

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