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CBFß-SMMHC Inhibition Triggers Apoptosis by Disrupting MYC Chromatin Dynamics in Acute Myeloid Leukemia.
Pulikkan, John Anto; Hegde, Mahesh; Ahmad, Hafiz Mohd; Belaghzal, Houda; Illendula, Anuradha; Yu, Jun; O'Hagan, Kelsey; Ou, Jianhong; Muller-Tidow, Carsten; Wolfe, Scot A; Zhu, Lihua Julie; Dekker, Job; Bushweller, John Hackett; Castilla, Lucio Hernán.
Afiliação
  • Pulikkan JA; Department of Molecular, Cell and Cancer Biology, University of Massachusetts Medical School, Worcester, MA, USA.
  • Hegde M; Department of Molecular, Cell and Cancer Biology, University of Massachusetts Medical School, Worcester, MA, USA.
  • Ahmad HM; Department of Molecular, Cell and Cancer Biology, University of Massachusetts Medical School, Worcester, MA, USA.
  • Belaghzal H; Howard Hughes Medical Institute, Program in Systems Biology, Department of Biochemistry and Molecular Pharmacology, University of Massachusetts Medical School, Worcester, MA, USA.
  • Illendula A; Department of Molecular Physiology and Biological Physics, University of Virginia, Charlottesville, VA, USA.
  • Yu J; Department of Molecular, Cell and Cancer Biology, University of Massachusetts Medical School, Worcester, MA, USA.
  • O'Hagan K; Department of Molecular, Cell and Cancer Biology, University of Massachusetts Medical School, Worcester, MA, USA.
  • Ou J; Department of Molecular, Cell and Cancer Biology, University of Massachusetts Medical School, Worcester, MA, USA.
  • Muller-Tidow C; Department of Medicine, Hematology, Oncology, and Rheumatology, University Hospital Heidelberg, Heidelberg, Germany.
  • Wolfe SA; Department of Molecular, Cell and Cancer Biology, University of Massachusetts Medical School, Worcester, MA, USA.
  • Zhu LJ; Department of Molecular, Cell and Cancer Biology, University of Massachusetts Medical School, Worcester, MA, USA.
  • Dekker J; Howard Hughes Medical Institute, Program in Systems Biology, Department of Biochemistry and Molecular Pharmacology, University of Massachusetts Medical School, Worcester, MA, USA.
  • Bushweller JH; Department of Molecular Physiology and Biological Physics, University of Virginia, Charlottesville, VA, USA.
  • Castilla LH; Department of Molecular, Cell and Cancer Biology, University of Massachusetts Medical School, Worcester, MA, USA. Electronic address: lucio.castilla@umassmed.edu.
Cell ; 174(1): 172-186.e21, 2018 06 28.
Article em En | MEDLINE | ID: mdl-29958106
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Cromatina / Proteínas de Fusão Oncogênica / Proteínas Proto-Oncogênicas c-myc / Apoptose Tipo de estudo: Prognostic_studies Idioma: En Ano de publicação: 2018 Tipo de documento: Article
Texto completo
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XML
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Cromatina / Proteínas de Fusão Oncogênica / Proteínas Proto-Oncogênicas c-myc / Apoptose Tipo de estudo: Prognostic_studies Idioma: En Ano de publicação: 2018 Tipo de documento: Article