Principles of Translational Control.
Cold Spring Harb Perspect Biol
; 11(9)2019 09 03.
Article
em En
| MEDLINE
| ID: mdl-29959195
ABSTRACT
Protein synthesis involves a complex machinery comprising numerous proteins and RNAs joined by noncovalent interactions. Its function is to link long chains of amino acids into proteins with precise sequences as encoded by the genome. Regulation of protein synthesis, called translational control, occurs both at a global level and at specific messenger RNAs (mRNAs). To understand how translation is regulated, knowledge of the molecular structures and kinetic interactions of its components is needed. This review focuses on the targets of translational control and the mechanisms employed.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Biossíntese de Proteínas
/
Regulação da Expressão Gênica
/
Genoma
Idioma:
En
Ano de publicação:
2019
Tipo de documento:
Article