Immune responses in the treatment of drug-sensitive pulmonary tuberculosis with phenylbutyrate and vitamin D<sub>3</sub> as host directed therapy.

Rekha, Rokeya Sultana; Mily, Akhirunnesa; Sultana, Tajnin; Haq, Ahsanul; Ahmed, Sultan; Mostafa Kamal, S M; van Schadewijk, Annemarie; Hiemstra, Pieter S; Gudmundsson, Gudmundur H; Agerberth, Birgitta; Raqib, Rubhana

Immune responses in the treatment of drug-sensitive pulmonary tuberculosis with phenylbutyrate and vitamin D₃ as host directed therapy.

Rekha, Rokeya Sultana; Mily, Akhirunnesa; Sultana, Tajnin; Haq, Ahsanul; Ahmed, Sultan; Mostafa Kamal, S M; van Schadewijk, Annemarie; Hiemstra, Pieter S; Gudmundsson, Gudmundur H; Agerberth, Birgitta; Raqib, Rubhana.

Afiliação

Rekha RS; Infectious Diseases Division, icddr,b, 68 Shaheed Tajuddin Ahmed Sarani, Dhaka, 1212, Bangladesh.
Mily A; Department of Laboratory Medicine, Clinical Microbiology, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden.
Sultana T; Infectious Diseases Division, icddr,b, 68 Shaheed Tajuddin Ahmed Sarani, Dhaka, 1212, Bangladesh.
Haq A; Department of Laboratory Medicine, Clinical Microbiology, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden.
Ahmed S; Infectious Diseases Division, icddr,b, 68 Shaheed Tajuddin Ahmed Sarani, Dhaka, 1212, Bangladesh.
Mostafa Kamal SM; Infectious Diseases Division, icddr,b, 68 Shaheed Tajuddin Ahmed Sarani, Dhaka, 1212, Bangladesh.
van Schadewijk A; Infectious Diseases Division, icddr,b, 68 Shaheed Tajuddin Ahmed Sarani, Dhaka, 1212, Bangladesh.
Hiemstra PS; Department of Laboratory Medicine, Clinical Microbiology, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden.
Gudmundsson GH; National Institute of the Diseases of the Chest and Hospital, Mohakhali, Dhaka, Bangladesh.
Agerberth B; Department of Pulmonology, Leiden University Medical Centre, Leiden, the Netherlands.
Raqib R; Department of Pulmonology, Leiden University Medical Centre, Leiden, the Netherlands.

BMC Infect Dis ; 18(1): 303, 2018 07 04.

Article em En | MEDLINE | ID: mdl-29973153

Assuntos

Tuberculose Pulmonar/imunologia; Vitamina D/uso terapêutico; Vitaminas/uso terapêutico; Adulto; Peptídeos Catiônicos Antimicrobianos/metabolismo; Colecalciferol; Citocinas/sangue; Estresse do Retículo Endoplasmático; Feminino; Humanos; Leucócitos Mononucleares; Macrófagos/imunologia; Masculino; Pessoa de Meia-Idade; Fenilbutiratos; RNA Mensageiro; Estudos Retrospectivos; Resultado do Tratamento; Tuberculose Pulmonar/tratamento farmacológico; Adulto Jovem; beta-Defensinas; Catelicidinas

Palavras-chave

Chemokines; Cytokines; Endoplasmic reticulum stress; Human beta-defensin-1 (HBD1); Mycobacterium tuberculosis

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Tuberculose Pulmonar / Vitamina D / Vitaminas Tipo de estudo: Diagnostic_studies / Observational_studies Limite: Adult / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2018 Tipo de documento: Article

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