BrainEXP: a database featuring with spatiotemporal expression variations and co-expression organizations in human brains.
Bioinformatics
; 35(1): 172-174, 2019 01 01.
Article
em En
| MEDLINE
| ID: mdl-29985970
ABSTRACT
Summary:
Gene expression changes over the lifespan and varies among different tissues or cell types. Gene co-expression also changes by sex, age, different tissues or cell types. However, gene expression under the normal state and gene co-expression in the human brain has not been fully defined and quantified. Here we present a database named Brain EXPression Database (BrainEXP) which provides spatiotemporal expression of individual genes and co-expression in normal human brains. BrainEXP consists of 4567 samples from 2863 healthy individuals gathered from existing public databases and our own data, in either microarray or RNA-Seq library types. We mainly provide two analysis results based on the large dataset (i) basic gene expression across specific brain regions, age ranges and sexes; (ii) co-expression analysis from different platforms. Availability and implementation http//www.brainexp.org/. Supplementary information Supplementary data are available at Bioinformatics online.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Encéfalo
/
Perfilação da Expressão Gênica
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Bases de Dados Genéticas
Limite:
Humans
Idioma:
En
Ano de publicação:
2019
Tipo de documento:
Article