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Identification of the First Synthetic Allosteric Modulator of the CB2 Receptors and Evidence of Its Efficacy for Neuropathic Pain Relief.
Gado, Francesca; Di Cesare Mannelli, Lorenzo; Lucarini, Elena; Bertini, Simone; Cappelli, Elena; Digiacomo, Maria; Stevenson, Lesley A; Macchia, Marco; Tuccinardi, Tiziano; Ghelardini, Carla; Pertwee, Roger G; Manera, Clementina.
Afiliação
  • Gado F; Department of Pharmacy , University of Pisa , 56126 Pisa , Italy.
  • Di Cesare Mannelli L; Department of Neuroscience, Psychology, Drug Research and Child Health, Section of Pharmacology and Toxicology , University of Florence , 50139 Florence , Italy.
  • Lucarini E; Department of Neuroscience, Psychology, Drug Research and Child Health, Section of Pharmacology and Toxicology , University of Florence , 50139 Florence , Italy.
  • Bertini S; Department of Pharmacy , University of Pisa , 56126 Pisa , Italy.
  • Cappelli E; Department of Pharmacy , University of Pisa , 56126 Pisa , Italy.
  • Digiacomo M; Department of Pharmacy , University of Pisa , 56126 Pisa , Italy.
  • Stevenson LA; School of Medicine, Medical Sciences and Nutrition, Institute of Medical Sciences , University of Aberdeen , AB25 2ZD Aberdeen , Scotland, U.K.
  • Macchia M; Department of Pharmacy , University of Pisa , 56126 Pisa , Italy.
  • Tuccinardi T; Department of Pharmacy , University of Pisa , 56126 Pisa , Italy.
  • Ghelardini C; Sbarro Institute for Cancer Research and Molecular Medicine, Center for Biotechnology, College of Science and Technology , Temple University , Philadelphia , Pennsylvania 19122 , United States.
  • Pertwee RG; Department of Neuroscience, Psychology, Drug Research and Child Health, Section of Pharmacology and Toxicology , University of Florence , 50139 Florence , Italy.
  • Manera C; School of Medicine, Medical Sciences and Nutrition, Institute of Medical Sciences , University of Aberdeen , AB25 2ZD Aberdeen , Scotland, U.K.
J Med Chem ; 62(1): 276-287, 2019 01 10.
Article em En | MEDLINE | ID: mdl-29990428
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Receptor CB2 de Canabinoide / Amidas / Analgésicos Tipo de estudo: Diagnostic_studies / Prognostic_studies Limite: Animals Idioma: En Ano de publicação: 2019 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Receptor CB2 de Canabinoide / Amidas / Analgésicos Tipo de estudo: Diagnostic_studies / Prognostic_studies Limite: Animals Idioma: En Ano de publicação: 2019 Tipo de documento: Article