Topology of signal recognition particle receptor in endoplasmic reticulum membrane.
Nature
; 318(6044): 334-8, 1985.
Article
em En
| MEDLINE
| ID: mdl-2999608
ABSTRACT
The signal recognition particle (SRP) receptor is an integral membrane protein of the endoplasmic reticulum which, in conjunction with SRP, ensures the correct targeting of nascent secretory proteins to this membrane system. From the complementary DNA sequence we have deduced the complete primary structure of the SRP receptor and established that its amino-terminal region is anchored in the membrane. The anchor fragment and the cytoplasmic fragment contribute jointly to a functionally important region which is highly charged and may function in nucleic acid binding.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Sinais Direcionadores de Proteínas
/
Receptores de Peptídeos
/
Receptores Citoplasmáticos e Nucleares
/
Receptores de Superfície Celular
/
Retículo Endoplasmático
/
Proteínas de Membrana
Limite:
Animals
Idioma:
En
Ano de publicação:
1985
Tipo de documento:
Article