Surface-Assisted Self-Assembly of a Hydrogel by Proton Diffusion.
Angew Chem Int Ed Engl
; 57(35): 11349-11353, 2018 08 27.
Article
em En
| MEDLINE
| ID: mdl-29999232
ABSTRACT
Controlling supramolecular growth at solid surfaces is of great importance to expand the scope of supramolecular materials. A dendritic benzene-1,3,5-tricarboxamide peptide conjugate is described in which assembly can be triggered by a pH jump. Stopped-flow kinetics and mathematical modeling provide a quantitative understanding of the nucleation, elongation, and fragmentation behavior in solution. To assemble the molecule at a solid-liquid interface, we use proton diffusion from the bulk. The latter needs to be slower than the lag phase of nucleation to progressively grow a hydrogel outwards from the surface. Our method of surface-assisted self-assembly is generally applicable to other gelators, and can be used to create structured supramolecular materials.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Idioma:
En
Ano de publicação:
2018
Tipo de documento:
Article