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Bone Marrow-Derived and Adipose-Derived Mesenchymal Stem Cell Therapy in Primary Knee Osteoarthritis: A Narrative Review.
Jayaram, Prathap; Ikpeama, Uzoh; Rothenberg, Joshua B; Malanga, Gerard A.
Afiliação
  • Jayaram P; H. Ben Taub Dept of Physical Medicine & Rehabilitation, Orthopedic Surgery, Baylor College of Medicine, 1 Baylor Plaza, Houston, TX 77030.
  • Ikpeama U; H. Ben Taub Dept of Physical Medicine & Rehabilitation, Baylor College of Medicine, Houston, TX.
  • Rothenberg JB; Departments of Regenerative Medicine and Orthopedic Biologics, BocaCare Orthopedics, Boca Raton Regional Hospital, Boca Raton, FL.
  • Malanga GA; Department of Physical Medicine and Rehabilitation, Rutgers School of Biomedical and Health Sciences, Newark, NJ; Rutgers University and New Jersey Regenerative Medicine Institute, Cedar Knolls, NJ.
PM R ; 11(2): 177-191, 2019 02.
Article em En | MEDLINE | ID: mdl-30010050
ABSTRACT
Regenerative medicine in the context of musculoskeletal injury is a broad term that offers potential therapeutic solutions to restore or repair damaged tissue. The current focus in recent literature and clinical practice has been on cell based therapy. In particular, much attention has been centered on autologous bone marrow concentrate and adipose-derived mesenchymal stem cells (MSCs) for cartilage and tendon disorders. This article provides an overview of MSC-derived therapy and offers a comprehensive review of adipose- and bone marrow-derived MSC therapy in primary knee osteoarthritis. LEVEL OF EVIDENCE IV.
Assuntos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Células da Medula Óssea / Tecido Adiposo / Transplante de Medula Óssea / Osteoartrite do Joelho / Transplante de Células-Tronco Mesenquimais / Medicina Regenerativa Limite: Humans Idioma: En Ano de publicação: 2019 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Células da Medula Óssea / Tecido Adiposo / Transplante de Medula Óssea / Osteoartrite do Joelho / Transplante de Células-Tronco Mesenquimais / Medicina Regenerativa Limite: Humans Idioma: En Ano de publicação: 2019 Tipo de documento: Article