Ancylostoma ceylanicum Hookworm in Myanmar Refugees, Thailand, 2012-2015.
Emerg Infect Dis
; 24(8)2018 08.
Article
em En
| MEDLINE
| ID: mdl-30014834
ABSTRACT
During 2012-2015, US-bound refugees living in Myanmar-Thailand border camps (n = 1,839) were surveyed for hookworm infection and treatment response by using quantitative PCR. Samples were collected at 3 time points after each of 2 treatments with albendazole and after resettlement in the United States. Baseline prevalence of Necator americanus hookworm was 25.4%, Ancylostoma duodenale 0%, and Ancylostoma ceylanicum (a zoonosis) 5.4%. Compared with N. americanus prevalence, A. ceylanicum hookworm prevalence peaked in younger age groups, and blood eosinophil concentrations during A. ceylanicum infection were higher than those for N. americanus infection. Female sex was associated with a lower risk for either hookworm infection. Cure rates after 1 dose of albendazole were greater for A. ceylanicum (93.3%) than N. americanus (65.9%) hookworm (p<0.001). Lower N. americanus hookworm cure rates were unrelated to ß-tubulin single-nucleotide polymorphisms at codons 200 or 167. A. ceylanicum hookworm infection might be more common in humans than previously recognized.
Palavras-chave
Ancylostoma; Ancylostoma ceylanicum; Ancylostoma duodenale; Burmese; Myanmar; Necator americanus; SNP167; SNP200; Thailand; United States; albendazole; benzimidazole; cure rate; eosinophils; hemoglobin; hookworm; neglected tropical disease; parasites; refugees; soil-transmitted helminths; zoonoses; ß-tubulin SNP
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Refugiados
/
Ancylostoma
/
Ancilostomíase
Tipo de estudo:
Risk_factors_studies
Limite:
Adolescent
/
Adult
/
Aged
/
Aged80
/
Animals
/
Child
/
Child, preschool
/
Female
/
Humans
/
Infant
País/Região como assunto:
Asia
Idioma:
En
Ano de publicação:
2018
Tipo de documento:
Article