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Structural Basis of Substrate Recognition and Covalent Inhibition of Cdu1 from Chlamydia trachomatis.
Ramirez, Yesid A; Adler, Thomas B; Altmann, Eva; Klemm, Theresa; Tiesmeyer, Christian; Sauer, Florian; Kathman, Stefan G; Statsyuk, Alexander V; Sotriffer, Christoph; Kisker, Caroline.
Afiliação
  • Ramirez YA; Rudolf Virchow Center for Experimental Biomedicine, Institute of Structural Biology, University of Würzburg, Josef-Schneider-Straße 2, 97080, Würzburg, Germany.
  • Adler TB; Institute of Pharmacy and Food Chemistry, University of Würzburg, Am Hubland, 97074, Würzburg, Germany.
  • Altmann E; Institute of Pharmacy and Food Chemistry, University of Würzburg, Am Hubland, 97074, Würzburg, Germany.
  • Klemm T; Novartis Institute for Biomedical Research, Novartis Campus, 4002, Basel, Switzerland.
  • Tiesmeyer C; Rudolf Virchow Center for Experimental Biomedicine, Institute of Structural Biology, University of Würzburg, Josef-Schneider-Straße 2, 97080, Würzburg, Germany.
  • Sauer F; Rudolf Virchow Center for Experimental Biomedicine, Institute of Structural Biology, University of Würzburg, Josef-Schneider-Straße 2, 97080, Würzburg, Germany.
  • Kathman SG; Rudolf Virchow Center for Experimental Biomedicine, Institute of Structural Biology, University of Würzburg, Josef-Schneider-Straße 2, 97080, Würzburg, Germany.
  • Statsyuk AV; Northwestern University, Department of Chemistry, Silverman Hall, Sheridan Road 2145, Evanston, 60208, IL, USA.
  • Sotriffer C; University of Houston, College of Pharmacy, 4849 Calhoun Road, Houston, 77204, TX, USA.
  • Kisker C; Institute of Pharmacy and Food Chemistry, University of Würzburg, Am Hubland, 97074, Würzburg, Germany.
ChemMedChem ; 13(19): 2014-2023, 2018 10 08.
Article em En | MEDLINE | ID: mdl-30028574

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Pirimidinas / Proteínas Fúngicas / Chlamydia trachomatis / Inibidores Enzimáticos / Enzimas Desubiquitinantes Limite: Humans Idioma: En Ano de publicação: 2018 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Pirimidinas / Proteínas Fúngicas / Chlamydia trachomatis / Inibidores Enzimáticos / Enzimas Desubiquitinantes Limite: Humans Idioma: En Ano de publicação: 2018 Tipo de documento: Article