Natural products as sources of new fungicides (V): Design and synthesis of acetophenone derivatives against phytopathogenic fungi in vitro and in vivo.

Dan, Wen-Jia; Tuong, Thi-Mai-Luong; Wang, Da-Cheng; Li, Ding; Zhang, An-Ling; Gao, Jin-Ming

Dan, Wen-Jia; Tuong, Thi-Mai-Luong; Wang, Da-Cheng; Li, Ding; Zhang, An-Ling; Gao, Jin-Ming.

Afiliação

Dan WJ; Shaanxi Key Laboratory of Natural Products & Chemical Biology, College of Chemistry & Pharmacy, Northwest A&F University, 22 Xinong Road, Yangling 712100, Shaanxi, China.
Tuong TM; Shaanxi Key Laboratory of Natural Products & Chemical Biology, College of Chemistry & Pharmacy, Northwest A&F University, 22 Xinong Road, Yangling 712100, Shaanxi, China.
Wang DC; Shaanxi Key Laboratory of Natural Products & Chemical Biology, College of Chemistry & Pharmacy, Northwest A&F University, 22 Xinong Road, Yangling 712100, Shaanxi, China.
Li D; Shaanxi Key Laboratory of Natural Products & Chemical Biology, College of Chemistry & Pharmacy, Northwest A&F University, 22 Xinong Road, Yangling 712100, Shaanxi, China.
Zhang AL; Shaanxi Key Laboratory of Natural Products & Chemical Biology, College of Chemistry & Pharmacy, Northwest A&F University, 22 Xinong Road, Yangling 712100, Shaanxi, China.
Gao JM; Shaanxi Key Laboratory of Natural Products & Chemical Biology, College of Chemistry & Pharmacy, Northwest A&F University, 22 Xinong Road, Yangling 712100, Shaanxi, China. Electronic address: jinminggao@nwsuaf.edu.cn.

Bioorg Med Chem Lett ; 28(17): 2861-2864, 2018 09 15.

Article em En | MEDLINE | ID: mdl-30037493

Assuntos

Acetofenonas/farmacologia; Ascomicetos/efeitos dos fármacos; Produtos Biológicos/farmacologia; Botrytis/efeitos dos fármacos; Fungicidas Industriais/farmacologia; Magnaporthe/efeitos dos fármacos; Acetofenonas/síntese química; Acetofenonas/química; Produtos Biológicos/síntese química; Produtos Biológicos/química; Relação Dose-Resposta a Droga; Desenho de Fármacos; Fungicidas Industriais/síntese química; Fungicidas Industriais/química; Concentração Inibidora 50; Testes de Sensibilidade Microbiana; Estrutura Molecular; Relação Estrutura-Atividade

Palavras-chave

Acetophenone derivatives; Antifungal activity; Natural products; Structureactivity relationship

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Acetofenonas / Ascomicetos / Produtos Biológicos / Botrytis / Magnaporthe / Fungicidas Industriais Tipo de estudo: Prognostic_studies Idioma: En Ano de publicação: 2018 Tipo de documento: Article

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