Mechanical loading induces primary cilia disassembly in tendon cells via TGFß and HDAC6.

Rowson, Daniel T; Shelton, Julia C; Screen, Hazel R C; Knight, Martin M

Rowson, Daniel T; Shelton, Julia C; Screen, Hazel R C; Knight, Martin M.

Afiliação

Rowson DT; Institute of Bioengineering and School of Engineering and Materials Science, Queen Mary University of London, London, United Kingdom. dtrowson@gmail.com.
Shelton JC; Institute of Bioengineering and School of Engineering and Materials Science, Queen Mary University of London, London, United Kingdom.
Screen HRC; Institute of Bioengineering and School of Engineering and Materials Science, Queen Mary University of London, London, United Kingdom. h.r.c.screen@qmul.ac.uk.
Knight MM; Institute of Bioengineering and School of Engineering and Materials Science, Queen Mary University of London, London, United Kingdom. m.m.knight@qmul.ac.uk.

Sci Rep ; 8(1): 11107, 2018 07 23.

Article em En | MEDLINE | ID: mdl-30038235

Assuntos

Cílios/metabolismo; Desacetilase 6 de Histona/metabolismo; Estresse Mecânico; Tendões/metabolismo; Tendões/patologia; Fator de Crescimento Transformador beta/metabolismo; Actinas/metabolismo; Animais; Matriz Extracelular/metabolismo; Humanos; Masculino; Pessoa de Meia-Idade; Ratos; Receptores de Fatores de Crescimento Transformadores beta/metabolismo; Tenócitos/metabolismo

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Estresse Mecânico / Tendões / Fator de Crescimento Transformador beta / Cílios / Desacetilase 6 de Histona Tipo de estudo: Risk_factors_studies Limite: Animals / Humans / Male / Middle aged Idioma: En Ano de publicação: 2018 Tipo de documento: Article

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