The Involvement of NLRP3 on the Effects of Minocycline in an AD-Like Pathology Induced by ß-Amyloid Oligomers Administered to Mice.

Garcez, Michelle Lima; Mina, Francielle; Bellettini-Santos, Tatiani; da Luz, Aline Pereira; Schiavo, Gustavo Luis; Macieski, Júlia Matias Carollo; Medeiros, Eduarda Behenck; Marques, Ariandne Oliveira; Magnus, Natália Quadros; Budni, Josiane

Garcez, Michelle Lima; Mina, Francielle; Bellettini-Santos, Tatiani; da Luz, Aline Pereira; Schiavo, Gustavo Luis; Macieski, Júlia Matias Carollo; Medeiros, Eduarda Behenck; Marques, Ariandne Oliveira; Magnus, Natália Quadros; Budni, Josiane.

Afiliação

Garcez ML; Laboratory of Experimental Neurology, Graduate Program in Health Sciences, University of Southern Santa Catarina (UNESC), Criciúma, SC, 88806-000, Brazil.
Mina F; Laboratory of Experimental Neurology, Graduate Program in Health Sciences, University of Southern Santa Catarina (UNESC), Criciúma, SC, 88806-000, Brazil.
Bellettini-Santos T; Laboratory of Experimental Neurology, Graduate Program in Health Sciences, University of Southern Santa Catarina (UNESC), Criciúma, SC, 88806-000, Brazil.
da Luz AP; Laboratory of Experimental Neurology, Graduate Program in Health Sciences, University of Southern Santa Catarina (UNESC), Criciúma, SC, 88806-000, Brazil.
Schiavo GL; Laboratory of Experimental Neurology, Graduate Program in Health Sciences, University of Southern Santa Catarina (UNESC), Criciúma, SC, 88806-000, Brazil.
Macieski JMC; Laboratory of Experimental Neurology, Graduate Program in Health Sciences, University of Southern Santa Catarina (UNESC), Criciúma, SC, 88806-000, Brazil.
Medeiros EB; Laboratory of Experimental Neurology, Graduate Program in Health Sciences, University of Southern Santa Catarina (UNESC), Criciúma, SC, 88806-000, Brazil.
Marques AO; Laboratory of Experimental Neurology, Graduate Program in Health Sciences, University of Southern Santa Catarina (UNESC), Criciúma, SC, 88806-000, Brazil.
Magnus NQ; Laboratory of Experimental Neurology, Graduate Program in Health Sciences, University of Southern Santa Catarina (UNESC), Criciúma, SC, 88806-000, Brazil.
Budni J; Laboratory of Experimental Neurology, Graduate Program in Health Sciences, University of Southern Santa Catarina (UNESC), Criciúma, SC, 88806-000, Brazil. josiane.budni@unesc.net.

Mol Neurobiol ; 56(4): 2606-2617, 2019 Apr.

Article em En | MEDLINE | ID: mdl-30051350

Assuntos

Doença de Alzheimer/patologia; Peptídeos beta-Amiloides/administração & dosagem; Peptídeos beta-Amiloides/toxicidade; Minociclina/farmacologia; Proteína 3 que Contém Domínio de Pirina da Família NLR/metabolismo; Multimerização Proteica; Animais; Sobrevivência Celular/efeitos dos fármacos; Locomoção/efeitos dos fármacos; Masculino; Memória/efeitos dos fármacos; Camundongos Endogâmicos BALB C; Fator 88 de Diferenciação Mieloide/metabolismo; Neurônios/efeitos dos fármacos; Neurônios/metabolismo; Neurônios/patologia; Receptor 2 Toll-Like/metabolismo

Palavras-chave

Alzheimer's disease; Aß1-42 oligomers memory; Dementia; Inflammation; NLRP3

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Peptídeos beta-Amiloides / Multimerização Proteica / Doença de Alzheimer / Proteína 3 que Contém Domínio de Pirina da Família NLR / Minociclina Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Ano de publicação: 2019 Tipo de documento: Article

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