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Targeted delivery of CRISPR-Cas9 ribonucleoprotein into arthropod ovaries for heritable germline gene editing.
Chaverra-Rodriguez, Duverney; Macias, Vanessa M; Hughes, Grant L; Pujhari, Sujit; Suzuki, Yasutsugu; Peterson, David R; Kim, Donghun; McKeand, Sage; Rasgon, Jason L.
Afiliação
  • Chaverra-Rodriguez D; Department of Entomology, The Huck Institutes of the Life Sciences, and the Center for infectious Disease Dynamics, The Pennsylvania State University, University Park, PA, 16802, USA.
  • Macias VM; Department of Entomology, The Huck Institutes of the Life Sciences, and the Center for infectious Disease Dynamics, The Pennsylvania State University, University Park, PA, 16802, USA.
  • Hughes GL; Department of Entomology, The Huck Institutes of the Life Sciences, and the Center for infectious Disease Dynamics, The Pennsylvania State University, University Park, PA, 16802, USA.
  • Pujhari S; Department of Pathology, Institute for Human Infections and Immunity, Center for Tropical Diseases, Center for Biodefense and Emerging Infectious Disease, University of Texas Medical Branch, Galveston, TX, 77555, USA.
  • Suzuki Y; Department of Entomology, The Huck Institutes of the Life Sciences, and the Center for infectious Disease Dynamics, The Pennsylvania State University, University Park, PA, 16802, USA.
  • Peterson DR; Department of Entomology, The Huck Institutes of the Life Sciences, and the Center for infectious Disease Dynamics, The Pennsylvania State University, University Park, PA, 16802, USA.
  • Kim D; Institut Pasteur, Viruses and RNA Interference Unit, CNRS Unité Mixte de Recherche, 3569, Paris, France.
  • McKeand S; Department of Entomology, The Huck Institutes of the Life Sciences, and the Center for infectious Disease Dynamics, The Pennsylvania State University, University Park, PA, 16802, USA.
  • Rasgon JL; Department of Entomology, The Huck Institutes of the Life Sciences, and the Center for infectious Disease Dynamics, The Pennsylvania State University, University Park, PA, 16802, USA.
Nat Commun ; 9(1): 3008, 2018 08 01.
Article em En | MEDLINE | ID: mdl-30068905
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Ovário / Ribonucleoproteínas / Sistemas CRISPR-Cas / Edição de Genes / Proteína 9 Associada à CRISPR / Células Germinativas / Culicidae Limite: Animals Idioma: En Ano de publicação: 2018 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Ovário / Ribonucleoproteínas / Sistemas CRISPR-Cas / Edição de Genes / Proteína 9 Associada à CRISPR / Células Germinativas / Culicidae Limite: Animals Idioma: En Ano de publicação: 2018 Tipo de documento: Article