Progression of continuous downstream processing of monoclonal antibodies: Current trends and challenges.

Somasundaram, Balaji; Pleitt, Kristina; Shave, Evan; Baker, Kym; Lua, Linda H L

Somasundaram, Balaji; Pleitt, Kristina; Shave, Evan; Baker, Kym; Lua, Linda H L.

Afiliação

Somasundaram B; Australian Research Council Training Centre for Biopharmaceutical Innovation, Australian Institute for Bioengineering and Nanotechnology, The University of Queensland, Brisbane, Queensland, Australia.
Pleitt K; Australian Research Council Training Centre for Biopharmaceutical Innovation, Australian Institute for Bioengineering and Nanotechnology, The University of Queensland, Brisbane, Queensland, Australia.
Shave E; Australian Research Council Training Centre for Biopharmaceutical Innovation, Australian Institute for Bioengineering and Nanotechnology, The University of Queensland, Brisbane, Queensland, Australia.
Baker K; Patheon Biologics-a part of Thermo Fisher Scientific, Brisbane, Queensland, Australia.
Lua LHL; Patheon Biologics-a part of Thermo Fisher Scientific, Brisbane, Queensland, Australia.

Biotechnol Bioeng ; 115(12): 2893-2907, 2018 12.

Article em En | MEDLINE | ID: mdl-30080940

Assuntos

Anticorpos Monoclonais; Reatores Biológicos; Biotecnologia; Animais; Anticorpos Monoclonais/isolamento & purificação; Anticorpos Monoclonais/metabolismo; Biotecnologia/métodos; Biotecnologia/normas; Biotecnologia/tendências; Cromatografia; Humanos; Membranas Artificiais

Palavras-chave

continuous chromatography; continuous manufacturing; process scale-up and membrane adsorbers

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Biotecnologia / Reatores Biológicos / Anticorpos Monoclonais Limite: Animals / Humans Idioma: En Ano de publicação: 2018 Tipo de documento: Article

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