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Viral Teamwork Pushes CRISPR to the Breaking Point.
Nussenzweig, Philip M; Marraffini, Luciano A.
Afiliação
  • Nussenzweig PM; Laboratory of Bacteriology, The Rockefeller University, 1230 York Ave, New York, NY 10065, USA.
  • Marraffini LA; Laboratory of Bacteriology, The Rockefeller University, 1230 York Ave, New York, NY 10065, USA. Electronic address: marraffini@rockefeller.edu.
Cell ; 174(4): 772-774, 2018 08 09.
Article em En | MEDLINE | ID: mdl-30096306
Viruses have evolved inhibitors to counteract the CRISPR immune response, but they are not fully potent and need some time to be expressed after the beginning of infection. In this issue of Cell, Borges et al. and Landsberger et al. show that sequential infection gradually immunosuppresses the host to allow effective CRISPR inhibition.
Assuntos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Bacteriófagos / Vírus Idioma: En Ano de publicação: 2018 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Bacteriófagos / Vírus Idioma: En Ano de publicação: 2018 Tipo de documento: Article